{"id":"W2072363892","doi":"10.1016/j.molimm.2009.08.013","title":"Recombinant C3adesArg/acylation stimulating protein (ASP) is highly bioactive: A critical evaluation of C5L2 binding and 3T3-L1 adipocyte activation","year":2009,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut Universitaire de Cardiologie et de Pneumologie de Québec; McGill University; Université Laval","funders":"Canada Research Chairs","keywords":"Transfection; HEK 293 cells; Recombinant DNA; Receptor; Molecular biology; iC3b; Chinese hamster ovary cell; Biochemistry; Chemistry; Biology; Antibody; Complement system; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006201187,0.0001909632,0.0002230268,0.00013697,0.0001227287,0.00002764635,0.0001087195,0.0002943967,0.00005465325],"category_scores_gemma":[0.0004525053,0.0001986025,0.00008029864,0.000145561,0.00008179356,0.00001952314,0.00005663364,0.0001448445,0.000002964389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004796699,"about_ca_system_score_gemma":0.0000863438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002191383,"about_ca_topic_score_gemma":7.252521e-7,"domain_scores_codex":[0.9983985,0.0003046026,0.0003515518,0.0004242514,0.0002510768,0.0002699716],"domain_scores_gemma":[0.9991784,0.00002350602,0.0001779216,0.0002667281,0.0003117265,0.00004173171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001336956,0.00006739677,0.00004138943,0.00001228363,0.00006925117,0.000001374421,0.0001106912,0.0001214138,0.9735509,0.001383323,0.000007748326,0.0245005],"study_design_scores_gemma":[0.0009819817,0.0009445624,0.001058305,0.00007199254,0.000065467,0.00001189766,0.00008071543,0.003514304,0.9903418,0.002577392,0.0001448524,0.0002066658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9755495,0.000970553,0.02229482,0.0004132034,0.0001089394,0.0004627057,0.000004313664,0.00001475186,0.0001812223],"genre_scores_gemma":[0.9957874,0.00003189961,0.003872888,0.0001089355,0.0000353485,0.00003084077,0.00008201553,0.00002108072,0.00002956474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02429383,"threshold_uncertainty_score":0.8098774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01738040052574515,"score_gpt":0.2966896892095222,"score_spread":0.279309288683777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}