{"id":"W2072363892","doi":"10.1016/j.molimm.2009.08.013","title":"Recombinant C3adesArg/acylation stimulating protein (ASP) is highly bioactive: A critical evaluation of C5L2 binding and 3T3-L1 adipocyte activation","year":2009,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut Universitaire de Cardiologie et de Pneumologie de Québec; McGill University; Université Laval","funders":"Canada Research Chairs","keywords":"Transfection; HEK 293 cells; Recombinant DNA; Receptor; Molecular biology; iC3b; Chinese hamster ovary cell; Biochemistry; Chemistry; Biology; Antibody; Complement system; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006409343,0.0005350921,0.0001768534,0.0002635402,0.0003524979,0.0002754377,0.0003143343,0.0002972724,0.001293241],"category_scores_gemma":[0.0002734126,0.0001753072,0.0002328877,0.0003390556,0.0004432759,0.0002306773,0.0002213455,0.0005745879,0.000308207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006271316,"about_ca_system_score_gemma":0.0003165971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001845413,"about_ca_topic_score_gemma":0.001584024,"domain_scores_codex":[0.9997068,0.0001035095,0.0000226904,0.00003058456,0.00006640798,0.00007009433],"domain_scores_gemma":[0.9998142,0.00008634995,0.00002288749,0.00001966041,0.00002756412,0.00002933399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004756873,0.0000492702,0.00006374609,0.00001450019,0.000003203856,0.00006860952,0.00001496415,0.00009613253,0.9986362,0.0001194061,0.00002241327,0.000435844],"study_design_scores_gemma":[0.00001489887,0.0001817407,0.0002722813,7.191722e-7,0.000005359529,0.00006486902,0.00001039873,0.0003252049,0.9985787,0.00002035524,0.0005235803,0.00000190381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910215,0.0009154669,0.005153953,0.0001510989,0.00002991151,0.00007785027,0.0004847239,0.00005652509,0.002109088],"genre_scores_gemma":[0.9917961,0.0005297153,0.00439538,0.00005897209,0.00001368337,0.00003414221,0.00093098,0.00003347,0.002207614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001845413,"threshold_uncertainty_score":0.004550159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01738040052574515,"score_gpt":0.2966896892095222,"score_spread":0.279309288683777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}