{"id":"W2072470959","doi":"10.1074/jbc.m506921200","title":"Tyrosine 740 Phosphorylation of Discoidin Domain Receptor 2 by Src Stimulates Intramolecular Autophosphorylation and Shc Signaling Complex Formation","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Autophosphorylation; Proto-oncogene tyrosine-protein kinase Src; Tyrosine phosphorylation; Phosphorylation; Cell biology; Receptor tyrosine kinase; Chemistry; Tyrosine kinase; SH2 domain; Signal transduction; Tyrosine; Biology; Biochemistry; Protein kinase A","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004709638,0.0001349677,0.0003431897,0.00004308407,0.00004911343,0.00001992862,0.00009035074,0.0001855088,0.0006354438],"category_scores_gemma":[0.0002860665,0.00009691947,0.0001089366,0.0001430044,0.0001346841,0.0001015062,0.00004417939,0.0003080427,0.000004139069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001270853,"about_ca_system_score_gemma":0.0000400893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000193628,"about_ca_topic_score_gemma":6.985433e-8,"domain_scores_codex":[0.9986107,0.00005034866,0.000662596,0.000143516,0.000361426,0.0001714661],"domain_scores_gemma":[0.9989619,0.0001173183,0.00041096,0.0001026744,0.0002421838,0.000164927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005185459,0.0001557654,0.001270693,0.00008724742,0.00002806404,0.000007083203,0.00006507165,0.0001105326,0.9903398,0.000006327479,0.0007613809,0.0066495],"study_design_scores_gemma":[0.001290248,0.0004563295,0.00278614,0.0001128961,0.00002460521,0.00009066733,0.0001209268,0.002368664,0.9898913,0.0001197695,0.002638815,0.00009965547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993576,0.001675725,0.003558362,0.0008320073,0.00001338711,0.0001338308,0.00001340036,0.00001091344,0.0001863609],"genre_scores_gemma":[0.9909704,0.0002974893,0.008353164,0.0000711937,0.000115172,0.000001606739,0.0001229862,0.000009407257,0.0000585524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006549844,"threshold_uncertainty_score":0.6957664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02471705700444286,"score_gpt":0.2852249851936801,"score_spread":0.2605079281892372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}