{"id":"W2072518745","doi":"10.1016/j.jpba.2013.01.016","title":"Evaluating MISER chromatography for a rapid formulation screen","year":2013,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Chemistry; Chromatography; Flexibility (engineering); Mathematics; Statistics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003712257,0.0001049568,0.000221199,0.0001889142,0.00009644203,0.00004239496,0.00009490015,0.00009876896,0.0003886776],"category_scores_gemma":[0.000173644,0.00006934389,0.0004396595,0.000320712,0.00008545684,0.00001267421,0.00004654675,0.00007968831,0.000001925452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005082602,"about_ca_system_score_gemma":0.00002975517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009786411,"about_ca_topic_score_gemma":0.000001163248,"domain_scores_codex":[0.9989607,0.00006063941,0.0003907908,0.0001613028,0.0002504998,0.0001761226],"domain_scores_gemma":[0.9991056,0.00005755423,0.0001758995,0.00008127493,0.0002497797,0.0003298557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003071271,0.000328186,0.0103159,0.00006295824,0.002407802,0.000002099783,0.00002084698,0.00006488194,0.8796329,0.00003588706,0.01441174,0.09240971],"study_design_scores_gemma":[0.01974076,0.0153285,0.09517077,0.0002340608,0.01732684,0.0002527642,0.0004514492,0.2291584,0.2858358,0.006574574,0.3280201,0.001905917],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767976,0.001716852,0.02034557,0.0008149959,0.00009474762,0.0001570716,0.00001807442,0.000004304619,0.0000508249],"genre_scores_gemma":[0.9954037,0.0003127913,0.002948851,0.0007520929,0.0004739064,0.00001320361,0.00004584329,0.000006728097,0.00004288544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5937971,"threshold_uncertainty_score":0.4255747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03539646656444254,"score_gpt":0.3808306280630319,"score_spread":0.3454341614985893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}