{"id":"W2072522569","doi":"10.1016/j.bbamcr.2015.03.017","title":"N-linked Glycosylation of human SLC1A5 (ASCT2) transporter is critical for trafficking to membrane","year":2015,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada; Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Brefeldin A; Endocytosis; Biotinylation; Transport protein; Glycosylation; Cell biology; Mutant; Chemistry; Green fluorescent protein; Transfection; Cycloheximide; Biochemistry; Membrane protein; Molecular biology; Biology; Golgi apparatus; Membrane; Protein biosynthesis; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001283436,0.0002566839,0.0001423656,0.00008755208,0.0003025087,0.0003821094,0.0001468032,0.0004104897,0.001517022],"category_scores_gemma":[0.0002119787,0.0001375533,0.0003097437,0.00009060605,0.000193974,0.000273442,0.0002390358,0.0003458083,0.0006491721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005463249,"about_ca_system_score_gemma":0.0003632687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002163354,"about_ca_topic_score_gemma":0.002375643,"domain_scores_codex":[0.9998802,0.00002924776,0.00001282112,0.00003070157,0.0000246583,0.00002226846],"domain_scores_gemma":[0.9998717,0.00001685639,0.00003773024,0.00001239875,0.00001963748,0.0000415324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004486652,0.00001893544,0.001485007,0.00006263805,0.00001123154,0.0005905884,0.00003978726,0.0002131151,0.9943609,0.0005990097,0.0003484263,0.001821689],"study_design_scores_gemma":[0.00005244664,0.0001422101,0.02801722,0.00002679252,0.00004449726,0.003242859,0.0001299442,0.007994604,0.949239,0.000409055,0.01068525,0.0000161873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943246,0.001099708,0.002613155,0.0002917798,0.0000601519,0.00001178305,0.0002884311,0.00006058357,0.001249827],"genre_scores_gemma":[0.9963039,0.0002458777,0.001190974,0.0001081903,0.0000103115,0.000006229868,0.0005078111,0.00002343856,0.001603234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002163354,"threshold_uncertainty_score":0.005074978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07692673929004211,"score_gpt":0.3923366103130247,"score_spread":0.3154098710229826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}