{"id":"W2072522569","doi":"10.1016/j.bbamcr.2015.03.017","title":"N-linked Glycosylation of human SLC1A5 (ASCT2) transporter is critical for trafficking to membrane","year":2015,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada; Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Brefeldin A; Endocytosis; Biotinylation; Transport protein; Glycosylation; Cell biology; Mutant; Chemistry; Green fluorescent protein; Transfection; Cycloheximide; Biochemistry; Membrane protein; Molecular biology; Biology; Golgi apparatus; Membrane; Protein biosynthesis; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009812036,0.0003399749,0.0004291639,0.0002474101,0.0001546855,0.00006979099,0.0006197531,0.0003377553,0.00001988864],"category_scores_gemma":[0.0001975175,0.0003366479,0.0003540895,0.0004121147,0.0002923307,0.00001729055,0.0001884739,0.0003053659,0.00001813098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000339902,"about_ca_system_score_gemma":0.0002852167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005498925,"about_ca_topic_score_gemma":0.000009482764,"domain_scores_codex":[0.9967175,0.0002568321,0.0005143516,0.0008744705,0.00082596,0.0008109228],"domain_scores_gemma":[0.9977324,0.00006675941,0.00009766487,0.0008334703,0.0007802231,0.0004894902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004022097,0.0003333908,0.000002506845,0.0001322489,0.00006463248,0.000006003452,0.0005437422,0.00002288417,0.9948048,0.0007069989,0.00248789,0.0004927127],"study_design_scores_gemma":[0.001277209,0.001189035,0.0001639544,0.00003564847,0.00006525148,0.00000228564,0.0002042472,0.0001745184,0.9870743,0.0002048353,0.009231871,0.0003768408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913506,0.0003259291,0.003710345,0.001512276,0.0001154445,0.0009134292,0.0001257584,0.00002510491,0.001921129],"genre_scores_gemma":[0.9951805,0.00007232132,0.002876323,0.0005029872,0.0003168503,0.0001192695,0.0004054753,0.0001002379,0.0004259672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007730477,"threshold_uncertainty_score":0.9999086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07692673929004211,"score_gpt":0.3923366103130247,"score_spread":0.3154098710229826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}