{"id":"W2072535406","doi":"10.1016/s0378-1119(01)00723-5","title":"A repressor-response regulator gene pair controlling jadomycin B production in Streptomyces venezuelae ISP5230","year":2001,"lang":"en","type":"article","venue":"Gene","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Gene; Repressor; Regulator gene; Mutant; Response regulator; Genetics; Streptomyces; Plasmid; Gene cluster; Regulation of gene expression; Gene expression; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008750966,0.0002064912,0.0003959743,0.0001961372,0.00008551167,0.00002429375,0.0001041777,0.0001712325,0.0001619126],"category_scores_gemma":[0.0008888587,0.000165465,0.0001078125,0.0004259459,0.00006344981,0.0001047184,0.00003875868,0.0002688108,0.00004856877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001187073,"about_ca_system_score_gemma":0.00008730134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008652089,"about_ca_topic_score_gemma":0.00001614306,"domain_scores_codex":[0.9981678,0.0001799298,0.000401568,0.0006252465,0.0002342433,0.0003911704],"domain_scores_gemma":[0.9989842,0.00007214204,0.0001248467,0.0005867185,0.0001367516,0.00009535952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004256387,0.0001187359,0.005465826,0.00002995,0.00004876438,0.0002367004,0.000139868,0.00007573794,0.9772974,0.000002005992,0.003490524,0.00883816],"study_design_scores_gemma":[0.001421522,0.0001531193,0.03029579,0.0001028124,0.00006492963,0.000365247,0.0000442243,0.0000942456,0.9360588,0.00003904831,0.03116268,0.0001975495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9463118,0.001767528,0.00001134571,0.0508507,0.0002929208,0.0006141715,0.000007197918,0.0001006942,0.00004367613],"genre_scores_gemma":[0.9925266,0.0001614211,0.001391802,0.001927439,0.001148902,0.000006881042,0.00001979639,0.00002955416,0.002787607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04892327,"threshold_uncertainty_score":0.6747466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01544337980788175,"score_gpt":0.2513013554035184,"score_spread":0.2358579755956367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}