{"id":"W2072538486","doi":"10.1016/j.neurobiolaging.2009.09.001","title":"Reduced serine racemase expression contributes to age-related deficits in hippocampal cognitive function","year":2009,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Institut national de la recherche scientifique","keywords":"Hippocampal formation; NMDA receptor; Long-term potentiation; Serine; Hippocampus; Neuroscience; Glycine; Endocrinology; Excitatory postsynaptic potential; Internal medicine; Synaptic plasticity; Chemistry; Biology; Receptor; Biochemistry; Amino acid; Phosphorylation; Medicine; Inhibitory postsynaptic potential","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001145665,0.0001439428,0.0002326292,0.0001072386,0.00003722915,0.000004963636,0.00008967992,0.0001609955,0.000009136639],"category_scores_gemma":[0.0001211007,0.0001354465,0.00005616269,0.0001470225,0.00005720694,0.000004542935,0.00006396671,0.0001246274,0.000004979634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005125798,"about_ca_system_score_gemma":0.00002356258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006816711,"about_ca_topic_score_gemma":0.000005964059,"domain_scores_codex":[0.9990053,0.0001074595,0.0002632089,0.0003380483,0.00003733349,0.0002486236],"domain_scores_gemma":[0.9996175,0.00002421326,0.00009062618,0.0001511417,0.00006466012,0.00005190498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002811927,0.00005591554,0.001117068,0.000004846723,0.0000139004,0.000006571986,0.00005139658,0.0001598225,0.9953051,0.00006516247,0.0002358649,0.002703209],"study_design_scores_gemma":[0.001241766,0.0005148291,0.1209116,0.00005940738,0.00002476115,0.000009830225,0.00006317008,0.000007063022,0.8760485,0.0001352712,0.0008533315,0.0001303999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976699,0.0007482008,0.0004068378,0.0003169792,0.0002591024,0.0002210322,0.000009360367,0.00001517014,0.0003533932],"genre_scores_gemma":[0.9985007,0.00007788994,0.0001284662,0.0009165767,0.00005514042,0.000008660095,0.0001364206,0.00001055505,0.0001655827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1197946,"threshold_uncertainty_score":0.5523349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007345232296495338,"score_gpt":0.2449872795278565,"score_spread":0.2376420472313612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}