{"id":"W2072554644","doi":"10.1016/j.bbr.2015.02.035","title":"Mice deficient in carbonic anhydrase type 8 exhibit motor dysfunctions and abnormal calcium dynamics in the somatic region of cerebellar granule cells","year":2015,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Cerebellum; Granule cell; Calcium; Somatic cell; Calcium imaging; Biology; Neuroscience; Calcium in biology; Glutamate receptor; GABAergic; Purkinje cell; Endocrinology; Internal medicine; Cell biology; Chemistry; Intracellular; Central nervous system; Genetics; Inhibitory postsynaptic potential; Gene; Medicine; Dentate gyrus; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002030299,0.001556347,0.0006000255,0.0015269,0.0003587283,0.000560687,0.0007329177,0.001313305,0.003784433],"category_scores_gemma":[0.0003862602,0.0005600172,0.0003988595,0.0004389531,0.00116104,0.0004719772,0.0005240244,0.001389004,0.001085234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004639618,"about_ca_system_score_gemma":0.0003409482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001472631,"about_ca_topic_score_gemma":0.002844984,"domain_scores_codex":[0.999652,0.00002708852,0.00004681875,0.0001132664,0.0001053487,0.00005541532],"domain_scores_gemma":[0.9988924,0.0001207487,0.0006102069,0.00006690823,0.00005677069,0.0002530831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002039977,0.00002808265,0.0003364621,0.00002846592,0.00001644748,0.0003100196,0.00003316859,0.00008842596,0.9978229,0.0002355416,0.00009052042,0.000806121],"study_design_scores_gemma":[0.0002299128,0.0003779798,0.02292374,0.00003700657,0.0001581608,0.004641363,0.0001890131,0.001939323,0.9649845,0.0006975133,0.003785337,0.00003610315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891788,0.0007437818,0.006204951,0.0003044549,0.00007313729,0.00002773295,0.001505337,0.0006370251,0.001324863],"genre_scores_gemma":[0.9795982,0.0009510109,0.005658289,0.0001292204,0.00004038819,0.00008740905,0.001451755,0.0003648286,0.01171883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003784433,"threshold_uncertainty_score":0.01266015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09947421804110626,"score_gpt":0.3347226675033985,"score_spread":0.2352484494622923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}