{"id":"W2072573783","doi":"10.1016/j.cyto.2009.07.490","title":"Induction of neutrophil degranulation by S100A9 via a MAPK-dependent mechanism","year":2009,"lang":"en","type":"article","venue":"Cytokine","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Institut National de la Recherche Scientifique","funders":"","keywords":"Degranulation; S100A9; Mechanism (biology); MAPK/ERK pathway; Chemistry; Immunology; Medicine; Cell biology; Kinase; Biology; Inflammation; Biochemistry; Physics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007255017,0.0001004508,0.0001020576,0.00003394746,0.00003800874,0.000007308964,0.00008483132,0.0001211907,0.00002774537],"category_scores_gemma":[0.00001026204,0.00009448829,0.00005625467,0.00006490679,0.00001754879,0.000004159215,0.00002144602,0.00005482152,0.000005410443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009555443,"about_ca_system_score_gemma":0.00001401751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000213651,"about_ca_topic_score_gemma":0.00000453991,"domain_scores_codex":[0.9993905,0.00001992409,0.0001575504,0.0002003821,0.0001042856,0.0001273934],"domain_scores_gemma":[0.9996206,0.000001235339,0.00008006404,0.00019941,0.00005762971,0.00004110791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004908215,0.00007643644,0.00004255103,0.000004223162,0.000009682801,9.755024e-7,0.000009581011,0.00001644384,0.9895779,0.0004322136,0.0004495069,0.009331418],"study_design_scores_gemma":[0.0004582917,0.0005493563,0.001669931,0.000006910735,0.00001073223,0.0000117121,0.000009932741,0.00005852063,0.9920778,0.001508663,0.003529898,0.0001082684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806279,0.0002801872,0.0180826,0.0002353473,0.00009375145,0.0001496087,0.00002204881,0.00001414561,0.0004944458],"genre_scores_gemma":[0.9986365,0.00005910455,0.0004040522,0.000179526,0.0001894119,0.000006364673,0.0001686054,0.0000102436,0.0003461309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01800869,"threshold_uncertainty_score":0.3853121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006626649602897406,"score_gpt":0.2208812313177594,"score_spread":0.214254581714862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}