{"id":"W2072586423","doi":"10.1002/glia.20002","title":"The antiapoptotic effect of guanosine is mediated by the activation of the PI 3‐kinase/AKT/PKB pathway in cultured rat astrocytes","year":2004,"lang":"en","type":"article","venue":"Glia","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; McMaster University Medical Centre","funders":"Ministero dell'Università e della Ricerca","keywords":"Biology; Staurosporine; Guanosine; Protein kinase B; Cell biology; Adenosine; Protein kinase A; Kinase; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001204862,0.0003539106,0.0002692044,0.0001546042,0.0001775798,0.0001705749,0.0001231416,0.0001760181,0.0007593948],"category_scores_gemma":[0.00007543817,0.0001478447,0.0002515329,0.0001459232,0.0001700427,0.0001848889,0.0001598699,0.0004984406,0.0002661359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001600066,"about_ca_system_score_gemma":0.000355474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001198658,"about_ca_topic_score_gemma":0.002157636,"domain_scores_codex":[0.9999124,0.00001312161,0.00001006749,0.00001342045,0.00002546676,0.000025512],"domain_scores_gemma":[0.9999537,0.000005372379,0.00001358382,0.000006183228,0.000009806552,0.00001128342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002642381,0.00002456899,0.0001324393,0.00007044571,0.000005814405,0.0001051168,0.00002126924,0.00004452474,0.9978916,0.00005656365,0.00002871574,0.00135464],"study_design_scores_gemma":[0.00006491895,0.0007480942,0.00798505,0.00001451642,0.00002589378,0.0003210384,0.00004446832,0.0007061107,0.9880983,0.00009017764,0.001897175,0.000004214134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895149,0.005763224,0.002225563,0.000135275,0.00004723226,0.00002930344,0.000318228,0.00006440424,0.001901877],"genre_scores_gemma":[0.9903583,0.004517155,0.003049394,0.00005736357,0.00002049489,0.00006177581,0.0004166781,0.00001132278,0.001507367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001198658,"threshold_uncertainty_score":0.00254041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003890917859059052,"score_gpt":0.2151835088998674,"score_spread":0.2112925910408084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}