{"id":"W2072595228","doi":"10.1006/viro.2001.0815","title":"Analyzing the Mechanisms of Interferon-Induced Apoptosis Using CrmA and Hepatitis C Virus NS5A","year":2001,"lang":"en","type":"article","venue":"Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Protein kinase R; Biology; Interferon; Apoptosis; Virology; Innate immune system; FADD; NLRP1; Virus; Protein kinase A; RNA silencing; Programmed cell death; Caspase; Cell biology; Kinase; Immune system; RNA; Immunology; RNA interference; Gene; Mitogen-activated protein kinase kinase; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001832221,0.0001566993,0.0003233123,0.0001397819,0.000171023,0.00000754302,0.0002356803,0.0002626552,0.0005896565],"category_scores_gemma":[0.00007561287,0.0001156413,0.00009771497,0.0001350006,0.0002509389,0.00005787719,0.0002292016,0.0002511159,0.00004601279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002768332,"about_ca_system_score_gemma":0.00002987854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001216065,"about_ca_topic_score_gemma":0.0001852615,"domain_scores_codex":[0.9987301,0.0004245744,0.0002988958,0.0002218293,0.00001982578,0.0003048197],"domain_scores_gemma":[0.9993829,0.000120679,0.0001471584,0.0002948647,0.00004040114,0.00001399411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003982304,0.00004264184,0.002359693,0.000005225384,0.0001292789,0.000001853911,0.00018139,0.000001585203,0.9937304,0.001221655,0.00006843749,0.001859553],"study_design_scores_gemma":[0.0006135361,0.0005249308,0.01439863,0.00002610864,0.00006991101,0.0002957725,0.00009605104,0.00005394599,0.9821588,0.0004595162,0.001172889,0.0001299427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956391,0.0008104925,0.002039396,0.0002622233,0.0008023033,0.0001205107,0.00001142036,0.00002387424,0.0002906427],"genre_scores_gemma":[0.9989696,0.0002437643,0.00005849445,0.0002726323,0.0000128998,0.000005804506,0.000004035166,0.00001499039,0.000417765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01203894,"threshold_uncertainty_score":0.6456325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02196324028591293,"score_gpt":0.2581665281062684,"score_spread":0.2362032878203555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}