{"id":"W2072598705","doi":"10.1074/mcp.r500011-mcp200","title":"Integrating Global Proteomic and Genomic Expression Profiles Generated from Islet α Cells","year":2005,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Genome Canada","keywords":"Biology; Computational biology; Gene expression profiling; Gene; Proteomics; Gene expression; Islet; Molecular biology; Microarray; Phenotype; Shotgun; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001891871,0.0003422423,0.0004367843,0.0000701435,0.0001278743,0.00008856152,0.0001200063,0.0002340946,0.0001770596],"category_scores_gemma":[0.00009284357,0.000299163,0.0001184109,0.0001594305,0.00009556583,0.0000947695,0.0001167318,0.0002873391,0.0001220992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001934862,"about_ca_system_score_gemma":0.0001452931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008770737,"about_ca_topic_score_gemma":0.00000159288,"domain_scores_codex":[0.9982247,0.0001226395,0.0004253468,0.0005784776,0.0002634261,0.0003854036],"domain_scores_gemma":[0.9990327,0.00001812932,0.0001600442,0.0004440471,0.00009388668,0.0002512088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001370546,0.00009619896,0.001842101,0.00005059496,0.00006190984,0.00004767069,0.0001063276,0.00007815322,0.9955891,0.00009048116,0.0003069177,0.001593541],"study_design_scores_gemma":[0.001794754,0.000139296,0.0004192671,0.0001531178,0.0001138061,0.00001844912,0.0000649143,0.01047313,0.9852169,0.0002231525,0.001089025,0.0002941653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762518,0.001201887,0.01911672,0.0003938378,0.0001143096,0.001736291,0.00005437677,0.0001448533,0.0009859104],"genre_scores_gemma":[0.8420424,0.0000317061,0.156207,0.0007504949,0.0003017871,0.0001542137,0.0001981402,0.00004985507,0.0002644447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1370903,"threshold_uncertainty_score":0.9999461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007251351722050646,"score_gpt":0.2171963308188059,"score_spread":0.2099449790967552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}