{"id":"W2072599612","doi":"10.1097/01.tp.0000072373.77323.d4","title":"Alteration in CD45RBhi/CD45RBlo T-cell ratio following CD45RB monoclonal-antibody therapy occurs by selective deletion of CD45RBhi effector cells","year":2003,"lang":"en","type":"article","venue":"Transplantation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; London Health Sciences Centre","funders":"U.S. Public Health Service","keywords":"Monoclonal antibody; Cytotoxic T cell; Apoptosis; Cell biology; Biology; T cell; Cell; Molecular biology; CD8; Effector; Population; Antibody; In vitro; Immunology; Immune system; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003069446,0.0003981867,0.0005021807,0.0003056367,0.0001296417,0.0003665123,0.0001997659,0.0003006771,0.0008235096],"category_scores_gemma":[0.0001764883,0.0001715393,0.0002030034,0.0001263449,0.0001970548,0.0002165449,0.0001831462,0.0009185323,0.0002999807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001581518,"about_ca_system_score_gemma":0.0001279017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001222357,"about_ca_topic_score_gemma":0.0001836401,"domain_scores_codex":[0.9995542,0.00008877204,0.00006162926,0.00007468087,0.00008594158,0.0001348252],"domain_scores_gemma":[0.9997997,0.00003726719,0.00006928817,0.00002881026,0.00001528372,0.00004975452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001500432,0.00006785819,0.0002471367,0.00001834898,0.000002725245,0.00003091441,0.00001605004,0.0000253143,0.9982389,0.00004386919,0.000009757959,0.001148952],"study_design_scores_gemma":[0.00003438625,0.001019926,0.003434982,0.000005684501,0.00003236684,0.0003709241,0.0000166625,0.001040663,0.9930455,0.00003763076,0.0009581849,0.000003239478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950192,0.001158516,0.00272743,0.00004369914,0.00001986157,0.0000383546,0.00004710997,0.00008836111,0.0008574782],"genre_scores_gemma":[0.9961117,0.0003916871,0.002180088,0.00005957926,0.00001998804,0.00005600194,0.000118649,0.00002365526,0.001038778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008235096,"threshold_uncertainty_score":0.002754867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007199934046884952,"score_gpt":0.2362706673912537,"score_spread":0.2290707333443688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}