{"id":"W2072603692","doi":"10.1016/j.jmb.2011.03.071","title":"Study of Arachidonoyl Specificity in Two Enzymes of the PI Cycle","year":2011,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Phosphatidic acid; Phosphatidylinositol; Diacylglycerol kinase; Biochemistry; Gene isoform; Enzyme; Kinase; Pleckstrin homology domain; Residue (chemistry); Chemistry; Isozyme; Biology; Phospholipid; Protein kinase C; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001820487,0.0003132409,0.0002324735,0.0004511506,0.0003172876,0.0004260113,0.0003189599,0.0003983828,0.0007415299],"category_scores_gemma":[0.0003716036,0.0001990292,0.0002132473,0.0004211501,0.000322027,0.0003387259,0.0002460524,0.0006043594,0.0002802895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003842326,"about_ca_system_score_gemma":0.0003751182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00148918,"about_ca_topic_score_gemma":0.001411019,"domain_scores_codex":[0.9998764,0.000025957,0.000007601533,0.00002691679,0.00002458576,0.00003852764],"domain_scores_gemma":[0.9997806,0.0001044335,0.00001976027,0.0000252021,0.00002874374,0.00004122525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001148136,0.0000464654,0.001726785,0.00004326065,0.00001235433,0.0001699939,0.00007099502,0.0001193839,0.9919497,0.0009931417,0.00001776748,0.00370214],"study_design_scores_gemma":[0.0000521704,0.0002082967,0.009266325,0.000005911661,0.00003877929,0.0004163887,0.00006943946,0.001694108,0.986249,0.0005039794,0.001485497,0.00001005261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933276,0.001182607,0.00363978,0.00008347483,0.00001509716,0.00001518299,0.0001312828,0.00001159641,0.001593545],"genre_scores_gemma":[0.9958161,0.0005177284,0.001932087,0.00002423981,0.000007614283,0.00000871591,0.0004281415,0.000005574321,0.001259904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00148918,"threshold_uncertainty_score":0.00296098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01719461854207013,"score_gpt":0.2742114275571437,"score_spread":0.2570168090150736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}