{"id":"W2072605160","doi":"10.1016/j.exger.2008.05.001","title":"A role for altered TLR gene expression in association with increased expression of CD200R in the induction of mucosal tissue CD4+ Treg in aged mice following gavage with a liver extract along with intramuscular monophosphoryl lipid A (MPLA) injection","year":2008,"lang":"en","type":"article","venue":"Experimental Gerontology","topic":"Inflammation biomarkers and pathways","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"Prairie Research Institute","keywords":"FOXP3; Biology; Immunology; IL-2 receptor; Gene expression; Effector; Function (biology); Gene; Cell biology; Immune system; T cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001773527,0.0003689934,0.0003660804,0.0004210235,0.0001314905,0.0002325999,0.0001782485,0.000458226,0.002028181],"category_scores_gemma":[0.0001541147,0.0002135128,0.0002548402,0.0001367968,0.0003137821,0.0002858009,0.0001551604,0.000689561,0.0003079861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001766558,"about_ca_system_score_gemma":0.000142689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003689292,"about_ca_topic_score_gemma":0.0005757781,"domain_scores_codex":[0.9998662,0.00001875052,0.0000176572,0.00003715663,0.00001895144,0.00004119231],"domain_scores_gemma":[0.999773,0.0000206401,0.00008256581,0.00002611637,0.00002158112,0.00007610616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008146734,0.00003978744,0.000615173,0.00002088148,0.000003840467,0.00009148672,0.00001249443,0.000009119007,0.9977488,0.00002930417,0.00001688116,0.0005975965],"study_design_scores_gemma":[0.0000710271,0.001999607,0.0689708,0.00001346401,0.00007928089,0.0009667186,0.0001329228,0.0003881613,0.9262338,0.0001347038,0.0009979445,0.00001156886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976295,0.000806323,0.0007583168,0.00009207927,0.0000249596,0.0000095829,0.0002779082,0.00005227899,0.0003492143],"genre_scores_gemma":[0.9960533,0.0003250024,0.0008402604,0.0000710719,0.00001969243,0.00003266572,0.0002109723,0.00001240987,0.002434582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002028181,"threshold_uncertainty_score":0.006784916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01532118332602573,"score_gpt":0.238794917801561,"score_spread":0.2234737344755353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}