{"id":"W2072605525","doi":"10.1016/j.jaci.2005.12.566","title":"Signaling by the CysLT2 Receptor: Involvement of PKA, PKC and Downstream AP-1 and NF-kB Elements in IL-8 Gene Transcription","year":2006,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Protein kinase C; Chemistry; Transcription factor; NF-κB; Gene; Cell biology; Transcription (linguistics); Signal transduction; Receptor; Molecular biology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000437117,0.0005439931,0.00034756,0.0002522514,0.0003511529,0.0006737711,0.0003043715,0.0004943459,0.002116769],"category_scores_gemma":[0.0002924619,0.0002382619,0.0004675787,0.0001608747,0.0003114595,0.001020454,0.0003042525,0.0009497092,0.000533053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000543285,"about_ca_system_score_gemma":0.0004121114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004771518,"about_ca_topic_score_gemma":0.0005158534,"domain_scores_codex":[0.9997739,0.00003890093,0.00001831255,0.00004264533,0.00004180116,0.00008440934],"domain_scores_gemma":[0.9998301,0.00001810616,0.00003840169,0.00002386296,0.00003143306,0.00005803488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002470494,0.0001228005,0.0008121938,0.0001056785,0.00001461442,0.0003226763,0.00004340272,0.0001317583,0.9924605,0.0005438051,0.000203152,0.002768841],"study_design_scores_gemma":[0.0003775673,0.0006234646,0.02302176,0.00003507488,0.0000743046,0.00204779,0.0002552277,0.00229067,0.9661076,0.001096635,0.004041221,0.00002870011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806821,0.009429867,0.005518041,0.001253778,0.0001745103,0.00003199111,0.0004357117,0.0001141232,0.002359742],"genre_scores_gemma":[0.9923903,0.002225099,0.001973106,0.0001318025,0.00009375747,0.00003495484,0.000367495,0.00001726268,0.002766149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002116769,"threshold_uncertainty_score":0.00708127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01557809385570553,"score_gpt":0.2649086295592702,"score_spread":0.2493305357035647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}