{"id":"W2072615002","doi":"10.1089/thy.2009.0363","title":"Degradation of Thyroid Hormone Receptor Beta 1: Existence of Stable and Unstable Forms","year":2011,"lang":"en","type":"article","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Proteasome; Cycloheximide; Receptor; Protein degradation; Population; Ubiquitin; Cell biology; HEK 293 cells; Biology; Chemistry; Biochemistry; Molecular biology; Protein biosynthesis; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003241826,0.0002597628,0.0002921375,0.0004038274,0.0002484749,0.0006846253,0.0002140991,0.0002705735,0.001140061],"category_scores_gemma":[0.0003565215,0.0001571996,0.0003300851,0.0002518583,0.0002138627,0.0003654351,0.0001989041,0.0004053944,0.0005082776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005383172,"about_ca_system_score_gemma":0.0002653717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005058101,"about_ca_topic_score_gemma":0.0005689104,"domain_scores_codex":[0.9998148,0.00001764177,0.00001937194,0.0000587365,0.00004840181,0.00004097619],"domain_scores_gemma":[0.9996107,0.00007172182,0.0001255957,0.00004493402,0.00008670805,0.00006029156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003311908,0.00001799538,0.002888167,0.0000777713,0.00001845139,0.0001089128,0.00005506024,0.00003743163,0.9927145,0.0001672237,0.00005857936,0.003524625],"study_design_scores_gemma":[0.00004929259,0.000499929,0.06218284,0.00004597616,0.0001410162,0.003077807,0.0001694177,0.001470312,0.9247319,0.0005302769,0.007075425,0.00002590311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798283,0.01322211,0.005199862,0.0001403734,0.0000275905,0.00002322677,0.0005081418,0.00005097807,0.0009994084],"genre_scores_gemma":[0.9920505,0.002902211,0.002440893,0.00007309899,0.00002506706,0.00002706242,0.0008156862,0.00003225421,0.00163331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001140061,"threshold_uncertainty_score":0.003905773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02954810003514277,"score_gpt":0.243493185922728,"score_spread":0.2139450858875853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}