{"id":"W2072615002","doi":"10.1089/thy.2009.0363","title":"Degradation of Thyroid Hormone Receptor Beta 1: Existence of Stable and Unstable Forms","year":2011,"lang":"en","type":"article","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Proteasome; Cycloheximide; Receptor; Protein degradation; Population; Ubiquitin; Cell biology; HEK 293 cells; Biology; Chemistry; Biochemistry; Molecular biology; Protein biosynthesis; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001351184,0.0001496237,0.0003733832,0.00009649849,0.00004414351,0.000004212648,0.0000777939,0.00007183637,0.00009921748],"category_scores_gemma":[0.00002686822,0.0001155747,0.00006262115,0.000194021,0.0001311057,0.0001915866,0.00004741613,0.00007242733,0.00001504464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002537928,"about_ca_system_score_gemma":0.00005674973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005590948,"about_ca_topic_score_gemma":0.0000253059,"domain_scores_codex":[0.9990094,0.00001714593,0.0003278238,0.0002107943,0.0002135395,0.000221272],"domain_scores_gemma":[0.9992375,0.00002457511,0.000191086,0.000327356,0.000113739,0.0001057161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002976915,0.002491016,0.1175761,0.0003828579,0.0005072014,0.00001706444,0.003807241,0.000001121631,0.839821,0.0142377,0.005048376,0.01313339],"study_design_scores_gemma":[0.01291639,0.007885107,0.2278688,0.0001974955,0.0005952241,0.00005041251,0.003025507,0.0000840956,0.7402157,0.004974283,0.001681166,0.0005058286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9699652,0.00761413,0.0001827467,0.00006132251,0.00003254018,0.0003504438,0.00004366154,0.00002963816,0.02172039],"genre_scores_gemma":[0.990357,0.001323499,0.00583468,0.00002944952,0.00001123968,0.00001332833,0.00005846243,0.00002079162,0.002351559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1102927,"threshold_uncertainty_score":0.4713001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02954810003514277,"score_gpt":0.243493185922728,"score_spread":0.2139450858875853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}