{"id":"W2072630610","doi":"10.1016/s0264-410x(02)00694-1","title":"Super-activated interferon-regulatory factors can enhance plasmid immunization","year":2003,"lang":"en","type":"article","venue":"Vaccine","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McMaster University","funders":"","keywords":"IRF7; Immunization; Interferon regulatory factors; Biology; Vaccinia; Adjuvant; Virology; Plasmid; Antigen; Interferon; Antibody; Immunology; Recombinant DNA; Immune system; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001481246,0.0001679246,0.0002002484,0.000134805,0.0001610758,0.00001193128,0.0001257607,0.0001906996,0.001650205],"category_scores_gemma":[0.0001657298,0.0001454593,0.0000509819,0.0001849936,0.00001612751,0.0001520746,0.00002680232,0.0001902698,0.000293021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000698282,"about_ca_system_score_gemma":0.00005827481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006968135,"about_ca_topic_score_gemma":0.00002193156,"domain_scores_codex":[0.9990203,0.0002384862,0.000275097,0.0001870319,0.00002561221,0.0002534205],"domain_scores_gemma":[0.9994245,0.00009061644,0.00009250124,0.0003039324,0.00007371757,0.00001473382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001770426,0.00004378624,0.001988574,0.000006712751,0.00007546208,6.269119e-7,0.0006624409,0.00001111236,0.994487,0.0006661965,0.001147867,0.0007331938],"study_design_scores_gemma":[0.0006955217,0.0001410997,0.01320097,0.00002187309,0.0000139842,0.00001275707,0.0003266819,0.000001791497,0.94578,0.00002679229,0.03962239,0.0001560753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972025,0.00085196,0.0001851455,0.0001470814,0.0006448469,0.0001493506,0.000004520848,0.00009965365,0.0007148968],"genre_scores_gemma":[0.9959004,0.00006725203,0.00001422792,0.00005704822,0.00001093446,0.000009260676,0.0002708586,0.00002040464,0.003649635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04870692,"threshold_uncertainty_score":0.9992624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007594626158211688,"score_gpt":0.2188838416529316,"score_spread":0.2112892154947199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}