{"id":"W2072705074","doi":"10.1126/science.1095336","title":"Acidic Mammalian Chitinase in Asthmatic Th2 Inflammation and IL-13 Pathway Activation","year":2004,"lang":"en","type":"article","venue":"Science","topic":"Studies on Chitinases and Chitosanases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":806,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute","keywords":"Chitinase; Aeroallergen; Chemokine; Mediator; Asthma; Immunology; Inflammation; Interleukin 13; Biology; Chitin; Allergic inflammation; Allergy; Interleukin 4; Chemistry; Enzyme; Cell biology; Immune system; Allergen; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001708446,0.00008550704,0.00006791508,0.00006473748,0.0001464964,0.00003734877,0.0001141942,0.00003452588,0.000003117943],"category_scores_gemma":[0.0001744777,0.00007706159,0.00001752402,0.0002318236,0.0003215276,0.00001626645,0.00008794881,0.00004381442,0.000003632634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002042524,"about_ca_system_score_gemma":0.0001017158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005847026,"about_ca_topic_score_gemma":0.0005000699,"domain_scores_codex":[0.9992564,0.00001213333,0.0001253394,0.0002617671,0.0001491804,0.0001952061],"domain_scores_gemma":[0.9997011,0.000005879989,0.00005436483,0.0001520757,0.00003193779,0.00005457648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000176852,0.00002974021,0.004191991,0.00002101749,0.000002421826,0.000003711031,0.0002720871,0.0001931834,0.9831073,0.0007896653,0.000008365578,0.01136289],"study_design_scores_gemma":[0.0004284066,0.000139402,0.1429586,0.00003722495,0.000001536216,0.00001031085,0.0008459712,0.00002473104,0.8544474,0.0005431169,0.0004450762,0.0001181862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982616,0.0001104565,0.0001625115,0.000469718,0.00005294159,0.000116238,0.000004598862,0.000008454518,0.0008135228],"genre_scores_gemma":[0.9993859,0.00005597838,0.0003160534,0.0001058318,0.00008102378,0.00001388748,0.00001108659,0.000004839752,0.00002537919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1387666,"threshold_uncertainty_score":0.314248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007414456651016422,"score_gpt":0.2356317235819077,"score_spread":0.2282172669308913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}