{"id":"W2072705074","doi":"10.1126/science.1095336","title":"Acidic Mammalian Chitinase in Asthmatic Th2 Inflammation and IL-13 Pathway Activation","year":2004,"lang":"en","type":"article","venue":"Science","topic":"Studies on Chitinases and Chitosanases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":806,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute","keywords":"Chitinase; Aeroallergen; Chemokine; Mediator; Asthma; Immunology; Inflammation; Interleukin 13; Biology; Chitin; Allergic inflammation; Allergy; Interleukin 4; Chemistry; Enzyme; Cell biology; Immune system; Allergen; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002266547,0.000266077,0.0001463378,0.0001681992,0.0001315628,0.0001951292,0.0001086576,0.000360864,0.001234326],"category_scores_gemma":[0.00007788388,0.00008275213,0.0001385977,0.0001180238,0.0003032057,0.0001669187,0.0001386426,0.0004426792,0.000190415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002344698,"about_ca_system_score_gemma":0.0001859332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004528706,"about_ca_topic_score_gemma":0.0007507856,"domain_scores_codex":[0.9999087,0.0000299636,0.000004165228,0.000009727451,0.00002039085,0.00002703452],"domain_scores_gemma":[0.9999512,0.000006745458,0.00001063788,0.000003338263,0.000007593885,0.00002047367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008921794,0.00007321629,0.0009472363,0.00009439708,0.000008092391,0.0004807206,0.00002246701,0.00007805906,0.9910871,0.0005009943,0.000105436,0.005710188],"study_design_scores_gemma":[0.0003410265,0.002687628,0.08278812,0.00007062517,0.0000729491,0.004675098,0.0001975945,0.0016205,0.8905657,0.001405763,0.0155602,0.00001481665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9512907,0.03891763,0.002709514,0.0008724635,0.00009956707,0.00003582269,0.00009864385,0.00003707225,0.005938553],"genre_scores_gemma":[0.9915094,0.005026474,0.0007573885,0.00008502791,0.00003800334,0.00001516273,0.00006512262,0.000002795868,0.002500453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001234326,"threshold_uncertainty_score":0.004129231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007414456651016422,"score_gpt":0.2356317235819077,"score_spread":0.2282172669308913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}