{"id":"W2072996723","doi":"10.2147/ijn.s70828","title":"Characterization of the host&amp;ndash;guest complex of a curcumin analog with &amp;beta;-cyclodextrin and &amp;beta;-cyclodextrin&amp;ndash;gemini surfactant and evaluation of its anticancer activity","year":2015,"lang":"en","type":"article","venue":"International Journal of Nanomedicine","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Light Source (Canada); University of Saskatchewan","funders":"SLAC National Accelerator Laboratory; National Research Council Canada; National Institute of General Medical Sciences; Western Economic Diversification Canada; Biological and Environmental Research; Canadian Light Source; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Office of Science; National Institutes of Health; University of Saskatchewan; U.S. Department of Energy","keywords":"Cyclodextrin; Pulmonary surfactant; Thermogravimetric analysis; Beta-Cyclodextrins; Chemistry; Fourier transform infrared spectroscopy; Supramolecular chemistry; Drug delivery; Nanoparticle; Curcumin; Solubility; Nuclear chemistry; Dynamic light scattering; Materials science; Chemical engineering; Organic chemistry; Nanotechnology; Molecule; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003772196,0.0002664742,0.0007757667,0.0003640418,0.00007403447,0.00001860587,0.0004239008,0.0002016281,0.0002591774],"category_scores_gemma":[0.0004461374,0.0001888335,0.0001136318,0.0003484127,0.0006455453,0.000366086,0.0001389932,0.0004983823,0.000004491714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001677552,"about_ca_system_score_gemma":0.0004938392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001217209,"about_ca_topic_score_gemma":0.0002370965,"domain_scores_codex":[0.9960915,0.0008109127,0.00114875,0.000259337,0.001455156,0.000234367],"domain_scores_gemma":[0.9940213,0.000509494,0.002145351,0.0002364179,0.002848567,0.0002388945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002959308,0.000686242,0.1514133,0.0001972573,0.00103455,0.00000778826,0.002917081,0.0003819407,0.8352181,0.0001321758,0.0008310608,0.004221167],"study_design_scores_gemma":[0.01659617,0.0008864172,0.7779683,0.001322064,0.001764307,0.0009550052,0.0003469708,0.00245177,0.05941916,0.0001594826,0.1376004,0.0005298597],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926986,0.001311918,0.0008921505,0.002085837,0.00176459,0.0004849673,0.0003277472,0.000007753636,0.0004265094],"genre_scores_gemma":[0.9977171,0.0009870658,0.0001806546,0.0001862506,0.0004947765,0.000006406359,0.00007345623,0.00001896841,0.0003353393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7757989,"threshold_uncertainty_score":0.7700408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2290750267649534,"score_gpt":0.4458114905558231,"score_spread":0.2167364637908698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}