{"id":"W2072996723","doi":"10.2147/ijn.s70828","title":"Characterization of the host&amp;ndash;guest complex of a curcumin analog with &amp;beta;-cyclodextrin and &amp;beta;-cyclodextrin&amp;ndash;gemini surfactant and evaluation of its anticancer activity","year":2015,"lang":"en","type":"article","venue":"International Journal of Nanomedicine","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Light Source (Canada); University of Saskatchewan","funders":"SLAC National Accelerator Laboratory; National Research Council Canada; National Institute of General Medical Sciences; Western Economic Diversification Canada; Biological and Environmental Research; Canadian Light Source; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Office of Science; National Institutes of Health; University of Saskatchewan; U.S. Department of Energy","keywords":"Cyclodextrin; Pulmonary surfactant; Thermogravimetric analysis; Beta-Cyclodextrins; Chemistry; Fourier transform infrared spectroscopy; Supramolecular chemistry; Drug delivery; Nanoparticle; Curcumin; Solubility; Nuclear chemistry; Dynamic light scattering; Materials science; Chemical engineering; Organic chemistry; Nanotechnology; Molecule; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009756503,0.0001676189,0.0001343803,0.0001254631,0.00008822465,0.0001210658,0.0001059454,0.0001669497,0.0009316311],"category_scores_gemma":[0.0001947557,0.0000568502,0.000115135,0.0001144232,0.000134764,0.0001203166,0.00006996545,0.0001683032,0.0002029945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001988876,"about_ca_system_score_gemma":0.0001417666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005606932,"about_ca_topic_score_gemma":0.0007330138,"domain_scores_codex":[0.9999244,0.000007982631,0.000007770566,0.00001836011,0.00003093836,0.00001044212],"domain_scores_gemma":[0.9998746,0.00003217619,0.00003650195,0.000009938542,0.00002703094,0.00001969119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004865478,0.000008783877,0.0002108531,0.00001942367,0.00000205378,0.0000324389,0.000008555216,0.0000590761,0.9990381,0.00001546519,0.00001103981,0.0005455119],"study_design_scores_gemma":[0.000002806175,0.0001081439,0.001242267,0.00000143162,0.000004449922,0.00006216684,0.00001035822,0.0006059193,0.9973136,0.000005034758,0.0006413757,0.000002420728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967435,0.0004552367,0.001907706,0.00002409691,0.000009370857,0.00002536674,0.0001610729,0.00003507337,0.0006384936],"genre_scores_gemma":[0.9952999,0.0002602365,0.002809036,0.00001919428,0.000003406453,0.00002611891,0.0002827458,0.00001716891,0.001282138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009316311,"threshold_uncertainty_score":0.003116608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2290750267649534,"score_gpt":0.4458114905558231,"score_spread":0.2167364637908698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}