{"id":"W2073030164","doi":"10.1016/j.jsbmb.2015.03.006","title":"A low carbohydrate, high protein diet suppresses intratumoral androgen synthesis and slows castration-resistant prostate tumor growth in mice","year":2015,"lang":"en","type":"article","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency; University of British Columbia","funders":"","keywords":"LNCaP; Endocrinology; Internal medicine; Prostate cancer; Castration; Androgen; Prostate; Biology; Medicine; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002723506,0.0008589624,0.0004413834,0.001378473,0.0004754895,0.0006216445,0.0007446659,0.0006745932,0.002296137],"category_scores_gemma":[0.0001895269,0.000516444,0.0004781913,0.0005774194,0.001130261,0.0004681359,0.0003024536,0.001928082,0.0005030806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009798034,"about_ca_system_score_gemma":0.000976756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004010857,"about_ca_topic_score_gemma":0.008553077,"domain_scores_codex":[0.9996253,0.00005257315,0.00002827033,0.00006877632,0.00009268954,0.0001324043],"domain_scores_gemma":[0.9993122,0.00004578601,0.0001738077,0.00006365852,0.00003604855,0.00036851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004530059,0.0009185484,0.0004404408,0.00004524193,0.00002568,0.00007192306,0.00002736423,0.0001821948,0.991319,0.0003386597,0.0002943304,0.001806568],"study_design_scores_gemma":[0.0005922837,0.004431475,0.007518436,0.00001814366,0.00009393864,0.0002665592,0.00008637303,0.001562479,0.9821684,0.0002604536,0.002967126,0.000034358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949023,0.0006159286,0.001411149,0.0005456164,0.0001022301,0.00004365856,0.001015877,0.0003091411,0.00105409],"genre_scores_gemma":[0.9856967,0.0008427962,0.002698457,0.0002913231,0.00006633678,0.00013727,0.001292525,0.0001802278,0.008794286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004010857,"threshold_uncertainty_score":0.007975042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006243825434433782,"score_gpt":0.2212013073174525,"score_spread":0.2149574818830187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}