{"id":"W2073109018","doi":"10.1371/journal.pone.0039301","title":"Regulation of a Truncated Form of Tropomyosin-Related Kinase B (TrkB) by Hsa-miR-185* in Frontal Cortex of Suicide Completers","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Institut National de la Santé et de la Recherche Médicale; American Foundation for Suicide Prevention","keywords":"Tropomyosin receptor kinase B; microRNA; Gene silencing; Downregulation and upregulation; Biology; Molecular biology; Receptor; Neurotrophic factors; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001268912,0.0001175557,0.0002748302,0.00007843137,0.00001264962,0.00000178518,0.00009890521,0.000142835,0.00006533921],"category_scores_gemma":[0.00005583352,0.0001262083,0.00007518662,0.0001322288,0.0001120422,0.00001101605,0.00004227023,0.00004720782,0.000001864118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003728602,"about_ca_system_score_gemma":0.00003260701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001237953,"about_ca_topic_score_gemma":0.00002445608,"domain_scores_codex":[0.9989393,0.00005519648,0.0004789817,0.0001555727,0.000188782,0.0001821217],"domain_scores_gemma":[0.9992048,0.00001260562,0.0003415344,0.0002656382,0.0001148329,0.00006060932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002642215,0.001238218,0.02953781,0.0001238992,0.0001539741,1.523045e-7,0.0001270521,0.000009072311,0.9682297,0.00003968227,0.0001406049,0.0001355979],"study_design_scores_gemma":[0.0009430206,0.0001468287,0.2246031,0.00009162306,0.00007501043,6.808039e-7,0.00002872034,0.0003754457,0.7735834,0.00004274961,0.00001810173,0.00009136103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998383,0.0008861097,0.00009964958,0.0000218424,0.00001894543,0.0003157117,0.0001271639,0.000005862027,0.0001416463],"genre_scores_gemma":[0.9980839,0.00002245459,0.0006967816,0.00000909755,0.00001701533,0.000008968421,0.001086528,0.00001963372,0.00005555601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1950653,"threshold_uncertainty_score":0.5146626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01904510795648243,"score_gpt":0.2258489572943796,"score_spread":0.2068038493378971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}