{"id":"W2073119029","doi":"10.1111/xen.12133","title":"Systemic inflammation in xenograft recipients precedes activation of coagulation","year":2014,"lang":"en","type":"article","venue":"Xenotransplantation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; U.S. Public Health Service; Infrastructure Canada; National Institutes of Health; NIH Office of the Director; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; University of Pittsburgh","keywords":"Xenotransplantation; Medicine; Coagulation; Kidney; Immunology; Transplantation; Inflammation; Chemokine; Immunosuppression; Proinflammatory cytokine; Tissue factor; Kidney transplantation; CCL2; Heart transplantation; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003105315,0.0004444045,0.0004911464,0.0002651939,0.0001458473,0.0005025726,0.00009717479,0.0003103121,0.003437165],"category_scores_gemma":[0.0002638069,0.0001371307,0.0002691941,0.0001471732,0.0002828664,0.0003095218,0.0001674037,0.00128377,0.0005864383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001875292,"about_ca_system_score_gemma":0.0002010624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006658203,"about_ca_topic_score_gemma":0.00009760905,"domain_scores_codex":[0.9998325,0.00002190846,0.0000184598,0.00004848383,0.0000428092,0.00003583849],"domain_scores_gemma":[0.9994637,0.00007775112,0.0002097405,0.0000544072,0.00003677122,0.0001575657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002116413,0.0002290826,0.005001211,0.0001308563,0.0000164691,0.0006263034,0.00006651741,0.00005402652,0.98874,0.00009057521,0.0001183625,0.002810056],"study_design_scores_gemma":[0.0002733351,0.01942103,0.1372469,0.0001093754,0.000235306,0.01637737,0.0004154233,0.001689733,0.8193792,0.0002530104,0.004568767,0.00003060207],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958626,0.00135562,0.001380401,0.00004182152,0.00005599536,0.00003979039,0.0001657682,0.00007001784,0.001028002],"genre_scores_gemma":[0.9970091,0.0007230289,0.0008003941,0.00004663969,0.00004004371,0.00006811412,0.0003770924,0.00001537695,0.0009202913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003437165,"threshold_uncertainty_score":0.01149845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01304853712502888,"score_gpt":0.2677910575915745,"score_spread":0.2547425204665456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}