{"id":"W2073156871","doi":"10.1016/j.bbrc.2013.02.030","title":"SREBP-1a activation by HBx and the effect on hepatitis B virus enhancer II/core promoter","year":2013,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation","keywords":"HBx; Sterol regulatory element-binding protein; Transcription factor; Promoter; Ccaat-enhancer-binding proteins; Molecular biology; Enhancer; Ectopic expression; Biology; Leucine zipper; Transcription (linguistics); Hepatitis B virus; Gene; Chemistry; Gene expression; DNA-binding protein; Virus; Virology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003198903,0.0002621498,0.0002514269,0.0002521242,0.0002966065,0.0003221326,0.0002313293,0.000230605,0.003747238],"category_scores_gemma":[0.0002778367,0.0002368644,0.0003338108,0.0001642666,0.0004616257,0.0002616729,0.0002919042,0.0006922395,0.0004799382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004496848,"about_ca_system_score_gemma":0.0003965824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003201614,"about_ca_topic_score_gemma":0.002869439,"domain_scores_codex":[0.9997993,0.0000632693,0.00001345409,0.00002465118,0.00002904508,0.00007025281],"domain_scores_gemma":[0.9998199,0.00007438793,0.00001764063,0.00002548686,0.00001758292,0.00004489647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001701326,0.0000847698,0.0002522181,0.00003583137,0.000005721538,0.00003985033,0.00004733274,0.00006432741,0.9960017,0.0003857658,0.00005969131,0.001321463],"study_design_scores_gemma":[0.00005417506,0.0002582714,0.004821604,0.00000924596,0.000008652738,0.00007006362,0.00005798179,0.000618658,0.992945,0.0001259164,0.001024717,0.000005652691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949021,0.001432541,0.001294544,0.0001802739,0.00004650328,0.00001909756,0.0003939186,0.00004894998,0.001682169],"genre_scores_gemma":[0.9930719,0.000479418,0.001197255,0.00007652537,0.00001514702,0.00003144101,0.0007412275,0.00002571712,0.004361376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003747238,"threshold_uncertainty_score":0.01253569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05317352141348279,"score_gpt":0.3707260559203384,"score_spread":0.3175525345068556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}