{"id":"W2073156871","doi":"10.1016/j.bbrc.2013.02.030","title":"SREBP-1a activation by HBx and the effect on hepatitis B virus enhancer II/core promoter","year":2013,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation","keywords":"HBx; Sterol regulatory element-binding protein; Transcription factor; Promoter; Ccaat-enhancer-binding proteins; Molecular biology; Enhancer; Ectopic expression; Biology; Leucine zipper; Transcription (linguistics); Hepatitis B virus; Gene; Chemistry; Gene expression; DNA-binding protein; Virus; Virology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003933323,0.0001481769,0.0002658472,0.00005286587,0.0007148763,0.00006350117,0.0002777112,0.0001021124,0.00005009449],"category_scores_gemma":[0.00110623,0.00008429537,0.00005901544,0.0002852816,0.001991223,0.00008131286,0.0006485663,0.0006828964,0.00009114807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000659402,"about_ca_system_score_gemma":0.00002831079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004618333,"about_ca_topic_score_gemma":0.0000647026,"domain_scores_codex":[0.9984998,0.000283369,0.0001859033,0.0002770874,0.0004478343,0.0003060108],"domain_scores_gemma":[0.9971157,0.001616738,0.00003608888,0.0008207595,0.0002329107,0.0001777705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000200041,0.0002808789,0.001381656,0.00004825581,0.00006041712,2.93932e-7,0.0002236849,2.88711e-9,0.9587736,0.001443282,0.02105225,0.01653561],"study_design_scores_gemma":[0.002494828,0.002644268,0.03572344,0.0003677218,0.00006133012,0.000004188651,0.00003318618,0.001103702,0.9379835,0.00297623,0.01634623,0.0002613812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683969,0.0006954767,0.00000665576,0.02808743,0.000009162413,0.00115275,0.00002266119,0.00003448392,0.001594466],"genre_scores_gemma":[0.9946343,0.003265868,0.0001823124,0.000365037,0.00008894608,0.0007975656,0.00006296477,0.00001465494,0.0005883567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03434179,"threshold_uncertainty_score":0.7336743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05317352141348279,"score_gpt":0.3707260559203384,"score_spread":0.3175525345068556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}