{"id":"W2073184391","doi":"10.1371/journal.pone.0014447","title":"Comparative Analyses of SUV420H1 Isoforms and SUV420H2 Reveal Differences in Their Cellular Localization and Effects on Myogenic Differentiation","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Cancer Foundation; Alberta Health Services","keywords":"Biology; Myogenin; Heterochromatin; C2C12; Methyltransferase; Methylation; EZH2; Histone methylation; Chromatin; Histone H4; DNA methylation; Histone; Myogenesis; Population; Cell biology; Genetics; Myocyte; Gene expression; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006144105,0.0001067728,0.0002092286,0.00004967354,0.00003431485,0.00001596161,0.00005779814,0.00009487,0.000002268418],"category_scores_gemma":[0.00002437718,0.00008512911,0.00002115835,0.00004788589,0.00005959582,0.000003218353,0.00005784371,0.0000769304,2.714326e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003934098,"about_ca_system_score_gemma":0.00001083319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001748858,"about_ca_topic_score_gemma":0.0001306349,"domain_scores_codex":[0.9994591,0.00003576062,0.0001520979,0.0001846056,0.00007335227,0.00009509312],"domain_scores_gemma":[0.9996746,0.00002642526,0.000090125,0.0001350522,0.0000393081,0.00003447188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002728923,0.0002007115,0.1233642,0.00008483069,0.00007258105,1.788779e-7,0.0001636364,0.00001124322,0.8758917,0.00005451656,0.000001006921,0.0001281254],"study_design_scores_gemma":[0.0003115963,0.0002320197,0.2026574,0.00003771159,0.00003360655,2.699813e-7,0.00004352892,0.01054048,0.7856939,0.0003661283,3.417763e-7,0.00008304683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990956,0.0002217983,0.0004277543,0.00001918181,0.00001657792,0.0001778237,0.00001160345,0.000003277389,0.00002644837],"genre_scores_gemma":[0.9994305,0.0001226831,0.0002770509,0.00002199701,0.00002726294,0.00001007618,0.00009160565,0.000006730815,0.00001209702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09019778,"threshold_uncertainty_score":0.3471464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02459258283020425,"score_gpt":0.2356082445042431,"score_spread":0.2110156616740388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}