{"id":"W2073195235","doi":"10.1021/np030524n","title":"A New Antimalarial Quassinoid from<i>Simaba</i><i>o</i><i>rinocensis</i>","year":2004,"lang":"he","type":"article","venue":"Journal of Natural Products","topic":"Phytochemical compounds biological activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Plasmodium falciparum; IC50; Derivatization; Chemistry; Stereochemistry; Vero cell; Bark (sound); Traditional medicine; Biology; High-performance liquid chromatography; In vitro; Medicine; Biochemistry; Chromatography; Malaria; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006553447,0.0004474148,0.0002683395,0.0002564163,0.0001069659,0.0001911482,0.0001909,0.0001696824,0.001168954],"category_scores_gemma":[0.0000817464,0.00008807544,0.0002555548,0.0001718443,0.0001789681,0.0002192766,0.0001984452,0.0004414591,0.0003825998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001507197,"about_ca_system_score_gemma":0.0001449966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004281252,"about_ca_topic_score_gemma":0.0007947637,"domain_scores_codex":[0.9999565,0.000007343471,0.000003895925,0.00001008899,0.00001192079,0.00001017747],"domain_scores_gemma":[0.9999553,0.000003600691,0.0000148675,0.000003209768,0.00001175601,0.0000111327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001012996,0.00001300789,0.0002203187,0.0001385644,0.000007827517,0.00009994255,0.00001578788,0.00005761802,0.994149,0.0000820088,0.00005098806,0.005063669],"study_design_scores_gemma":[0.000130303,0.002757692,0.01303035,0.00004485167,0.0001599776,0.00170753,0.00009879236,0.0006007792,0.9383351,0.0002054551,0.04289946,0.00002973371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9604937,0.0189549,0.008888519,0.0002440499,0.0001023514,0.0000948167,0.0007446035,0.000472301,0.01000476],"genre_scores_gemma":[0.983085,0.005954125,0.006437695,0.0002154383,0.00006508212,0.00002716488,0.001411683,0.00002678449,0.002777148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001168954,"threshold_uncertainty_score":0.003910601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009500602886093158,"score_gpt":0.2311518819318569,"score_spread":0.2216512790457637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}