{"id":"W2073195235","doi":"10.1021/np030524n","title":"A New Antimalarial Quassinoid from<i>Simaba</i><i>o</i><i>rinocensis</i>","year":2004,"lang":"he","type":"article","venue":"Journal of Natural Products","topic":"Phytochemical compounds biological activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Plasmodium falciparum; IC50; Derivatization; Chemistry; Stereochemistry; Vero cell; Bark (sound); Traditional medicine; Biology; High-performance liquid chromatography; In vitro; Medicine; Biochemistry; Chromatography; Malaria; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003707831,0.0005938272,0.0009147617,0.0001035561,0.0001360584,0.0001683422,0.000879008,0.0005536948,0.00004441348],"category_scores_gemma":[0.001788181,0.0004581028,0.0005256225,0.0003620144,0.0003909853,0.000064315,0.0003890783,0.00136334,0.00004343754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001782233,"about_ca_system_score_gemma":0.001386054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000158403,"about_ca_topic_score_gemma":0.0000122584,"domain_scores_codex":[0.9966558,0.0001768875,0.00108076,0.0007506873,0.0006318616,0.0007040539],"domain_scores_gemma":[0.9970517,0.00008801123,0.001114652,0.0005762349,0.0007927564,0.0003766104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001930916,0.000344096,0.0001790197,0.00005590226,0.0004009283,0.00009786348,0.00006507905,0.00003315771,0.9712023,0.00004472495,0.02249656,0.003149422],"study_design_scores_gemma":[0.003525593,0.001386858,0.001018067,0.000213331,0.0001916696,0.0004748523,0.00005659888,0.000002013015,0.9571018,0.002600838,0.03283746,0.0005909675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9486728,0.03353638,0.0002572294,0.01184304,0.004960659,0.0002787034,0.00006249576,0.00001784154,0.0003708772],"genre_scores_gemma":[0.9757025,0.001060167,0.01197546,0.0009807048,0.009677366,8.844287e-7,0.00006933413,0.00004761644,0.0004859746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03247621,"threshold_uncertainty_score":0.9997871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009500602886093158,"score_gpt":0.2311518819318569,"score_spread":0.2216512790457637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}