{"id":"W2073212579","doi":"10.1007/s10549-014-2908-8","title":"Microsatellite genotyping reveals a signature in breast cancer exomes","year":2014,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McMaster University; National Science Foundation","keywords":"Breast cancer; Microsatellite; Genotyping; Biology; Exome; Microsatellite instability; Genetics; Exome sequencing; Cancer; Genotype; Allele; Gene; Mutation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000546017,0.0001846234,0.0003362332,0.001142624,0.0002599519,0.0004932549,0.0001760282,0.0005424708,0.001226841],"category_scores_gemma":[0.002328153,0.0001790481,0.000280715,0.000894865,0.0001114255,0.0001683236,0.000434483,0.0002399533,0.0005073923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002084035,"about_ca_system_score_gemma":0.0001240344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005322694,"about_ca_topic_score_gemma":0.00181672,"domain_scores_codex":[0.9993852,0.000111884,0.00006795276,0.0002032545,0.0001671157,0.00006459361],"domain_scores_gemma":[0.9991851,0.0003000379,0.0002411429,0.0001076584,0.0001151536,0.00005077554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009355858,0.00005431862,0.2032156,0.0002975763,0.0002935037,0.001080389,0.0003223392,0.001069033,0.7421156,0.000624047,0.001818542,0.04817329],"study_design_scores_gemma":[0.00006503694,0.0002538855,0.8582103,0.00007988192,0.0002973665,0.006237003,0.0002207572,0.01028375,0.1094493,0.002025808,0.01282888,0.00004800291],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820808,0.001048354,0.01021514,0.0002773854,0.00002981636,0.00003820404,0.004732128,0.0002435748,0.001334544],"genre_scores_gemma":[0.9768077,0.0004117093,0.01573186,0.0002881755,0.00001886585,0.00004787304,0.005443204,0.0000515178,0.001199052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001226841,"threshold_uncertainty_score":0.004104197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04183370506412432,"score_gpt":0.3616894598846556,"score_spread":0.3198557548205312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}