{"id":"W2073246990","doi":"10.1159/000024522","title":"Human Metastatic Prostate PC3 Cell Lines Degrade Bone Using Matrix Metalloproteinases","year":2000,"lang":"en","type":"article","venue":"Invasion and Metastasis","topic":"Bone health and treatments","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Manitoba; Hamilton Regional Laboratory Medicine Program","funders":"","keywords":"Matrix metalloproteinase; Chemistry; Bone resorption; Extracellular matrix; Cancer research; Matrix (chemical analysis); Cell biology; Bone cell; Cell culture; Prostate cancer; Endocrinology; Pathology; Internal medicine; Biochemistry; Cancer; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001867405,0.00067783,0.0003856044,0.0003186059,0.0003395005,0.0003642782,0.0002166174,0.0002653057,0.002832939],"category_scores_gemma":[0.0002132215,0.0001847347,0.0004174829,0.0003660083,0.0002548234,0.0001530528,0.0002333747,0.0008619152,0.001676513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003653103,"about_ca_system_score_gemma":0.0004536507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007176111,"about_ca_topic_score_gemma":0.01464115,"domain_scores_codex":[0.9997708,0.00002289867,0.00001228294,0.0000328285,0.0001125396,0.00004870272],"domain_scores_gemma":[0.9998866,0.00002633946,0.00001540778,0.00001791511,0.00003041413,0.00002334749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001191868,0.00008132337,0.0004839483,0.0001010025,0.00001167088,0.00009328991,0.00003730382,0.00008491585,0.9949716,0.0001660822,0.0005487368,0.003300888],"study_design_scores_gemma":[0.00003896034,0.0006664079,0.006830101,0.00001280416,0.00003832198,0.001057649,0.00003948938,0.0006403601,0.9773132,0.00009914167,0.01325154,0.00001221391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9164479,0.02868293,0.03158421,0.0009553006,0.0002399611,0.0003847634,0.007524804,0.0006982537,0.01348192],"genre_scores_gemma":[0.9381106,0.01318223,0.02308124,0.0002586688,0.0000622673,0.0002584817,0.01025968,0.00007109257,0.01471573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007176111,"threshold_uncertainty_score":0.01426864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06662631473781555,"score_gpt":0.3443005439197934,"score_spread":0.2776742291819779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}