{"id":"W2073276277","doi":"10.1016/s0167-4838(00)00087-x","title":"The role of tryptophan residues in substrate binding to catalytic domains A and B of xylanase C from Fibrobacter succinogenes S85","year":2000,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","topic":"Studies on Chitinases and Chitosanases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"Xylanase; Fibrobacter succinogenes; Chemistry; Residue (chemistry); Enzyme; Biochemistry; Tryptophan; Stereochemistry; Active site; Xylose; Fermentation; Amino acid; Rumen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000170967,0.0002419895,0.0002773331,0.000138133,0.000351246,0.0003138231,0.0003460183,0.0005383557,0.0007368178],"category_scores_gemma":[0.0003829366,0.0002014913,0.0002481177,0.0001224919,0.0002793505,0.0004128032,0.0002173464,0.0004134574,0.0003497389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002590333,"about_ca_system_score_gemma":0.0001552191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001600231,"about_ca_topic_score_gemma":0.00079518,"domain_scores_codex":[0.9999009,0.00002744553,0.000007487614,0.00002052813,0.00001864809,0.00002497662],"domain_scores_gemma":[0.9996957,0.0001569567,0.00004103759,0.00002654217,0.00003080446,0.00004910198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008824021,0.00007202803,0.001526208,0.00006483008,0.00001691979,0.0003097726,0.00008604643,0.0003822176,0.9932204,0.0004538533,0.00005707001,0.002928158],"study_design_scores_gemma":[0.00007423492,0.0004303706,0.0232767,0.00001691188,0.00003516311,0.0006166485,0.0002648461,0.007400064,0.9664247,0.0004386333,0.0009975696,0.00002416024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969285,0.0004144711,0.002174814,0.00003629063,0.000007271413,0.000005921864,0.00003741977,0.00001707757,0.0003782641],"genre_scores_gemma":[0.9990467,0.00007540192,0.000511043,0.00002185243,0.000002230347,0.000002996535,0.00005479917,0.000005547509,0.0002793637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001600231,"threshold_uncertainty_score":0.003181756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003320622123062738,"score_gpt":0.2154857099511724,"score_spread":0.2121650878281096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}