{"id":"W2073408104","doi":"10.1016/j.ymgme.2008.03.004","title":"Methionine synthase reductase deficiency results in adverse reproductive outcomes and congenital heart defects in mice","year":2008,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"National Institute of General Medical Sciences","keywords":"MTRR; Genetics; Biology; Internal medicine; Genotype; Medicine; Endocrinology; Gene; Methylenetetrahydrofolate reductase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004757596,0.0001761751,0.0003946728,0.0003393868,0.00005792593,0.0000100858,0.00005336978,0.000101414,0.000004300404],"category_scores_gemma":[0.0007434791,0.0001526981,0.00005068859,0.0004515481,0.0002057806,0.00004449678,0.00009683677,0.0002709016,0.000003994573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001833615,"about_ca_system_score_gemma":0.0001212112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003881184,"about_ca_topic_score_gemma":0.00006434716,"domain_scores_codex":[0.9983881,0.000122475,0.0003234503,0.0005495125,0.00027947,0.0003370493],"domain_scores_gemma":[0.9992938,0.00004949453,0.00003889416,0.0003222807,0.0001166405,0.0001789135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007687855,0.0006969931,0.05215281,0.00008082252,0.0000903347,0.003248992,0.002836641,0.00005634637,0.9365446,0.0002777682,0.0001582156,0.003087687],"study_design_scores_gemma":[0.005627762,0.0002169683,0.8508182,0.00003304426,0.00009869666,0.000488317,0.000266754,0.0001553813,0.1398841,0.000097828,0.002067562,0.000245338],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771302,0.02101767,0.000009888256,0.000869469,0.00006809898,0.0004538509,0.00002104208,0.00001026735,0.0004194585],"genre_scores_gemma":[0.994749,0.002561484,0.002178156,0.0002319051,0.00002948768,0.00001723656,0.00001688504,0.00001996978,0.0001958994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7986654,"threshold_uncertainty_score":0.6226849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0203065134598719,"score_gpt":0.2940536076884351,"score_spread":0.2737470942285632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}