{"id":"W2073518075","doi":"10.1371/journal.pntd.0000441","title":"Leishmania infantum Amastigotes Enhance HIV-1 Production in Cocultures of Human Dendritic Cells and CD4+ T Cells by Inducing Secretion of IL-6 and TNF-α","year":2009,"lang":"en","type":"article","venue":"PLoS neglected tropical diseases","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Leishmania infantum; Leishmania; Amastigote; Biology; Secretion; Dendritic cell; Chemokine; Virology; Macrophage; Immunology; Tumor necrosis factor alpha; Immune system; Cell biology; Visceral leishmaniasis; Leishmaniasis; In vitro; Parasite hosting","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002506679,0.000391273,0.0003492944,0.0002218858,0.0001248517,0.0004580048,0.0001494534,0.0002131632,0.001558876],"category_scores_gemma":[0.0002107821,0.0001453547,0.0003364423,0.0001824423,0.0001407354,0.0001387443,0.0003010351,0.0004956744,0.0004323876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001887454,"about_ca_system_score_gemma":0.0001542063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002998979,"about_ca_topic_score_gemma":0.0003910293,"domain_scores_codex":[0.9997404,0.00006398014,0.0000303329,0.00004757017,0.00005884528,0.00005879855],"domain_scores_gemma":[0.9998538,0.00005917968,0.00001727894,0.00001894589,0.00002395119,0.00002676756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003084154,0.0001196838,0.0006197431,0.0001348676,0.00001427156,0.0001053518,0.00004686921,0.00006883207,0.9961695,0.00004139267,0.00005925666,0.002311922],"study_design_scores_gemma":[0.00008090693,0.001654805,0.003835943,0.00001910435,0.00005011128,0.0003626564,0.00004342265,0.001001803,0.9904309,0.00003360784,0.002482465,0.000004244532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928745,0.002677631,0.002224811,0.00008520443,0.00008289867,0.00009384804,0.0002022969,0.00005390941,0.001704976],"genre_scores_gemma":[0.9935523,0.001209658,0.003272994,0.00007274544,0.00006749228,0.00008392968,0.0004027552,0.00001147985,0.001326588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001558876,"threshold_uncertainty_score":0.00521493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0115455572635187,"score_gpt":0.2656292840430423,"score_spread":0.2540837267795236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}