{"id":"W2073526926","doi":"10.1016/j.hrthm.2005.02.296","title":"The beneficial effects of a novel specific chymase inhibitor, SUNC8257, on congestive heart failure-related atrial remodeling in dogs","year":2005,"lang":"en","type":"article","venue":"Heart Rhythm","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Chymase; Heart failure; Medicine; Internal medicine; Cardiology; Ventricular remodeling; Angiotensin-converting enzyme; Angiotensin II; Renin–angiotensin system; Receptor; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003563112,0.0003701443,0.0008437524,0.0003047167,0.0002136805,0.0002322424,0.0002591296,0.0004224846,0.0007293212],"category_scores_gemma":[0.0003666635,0.0002067591,0.0002875498,0.0001094958,0.0007916556,0.0004555325,0.0001505499,0.0008357303,0.00012387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002265361,"about_ca_system_score_gemma":0.0002887182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003932877,"about_ca_topic_score_gemma":0.0008146857,"domain_scores_codex":[0.9998989,0.00002176344,0.00001395982,0.00002024254,0.00001357196,0.00003154432],"domain_scores_gemma":[0.9997674,0.0000644527,0.00004315758,0.00002601699,0.00001243622,0.00008663327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0768803,0.004437241,0.003512134,0.0004550186,0.0001820345,0.0006999692,0.0001337976,0.0009597007,0.866593,0.0004153711,0.0009407587,0.0447907],"study_design_scores_gemma":[0.01235811,0.1980186,0.05722051,0.0001049465,0.0008264608,0.001863111,0.0002909334,0.00767126,0.7152591,0.0004985117,0.0058001,0.0000882955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980898,0.001064792,0.0002406916,0.0001178936,0.00003848503,0.0000223303,0.00007433013,0.00002222414,0.0003293167],"genre_scores_gemma":[0.9975165,0.001080368,0.0005300228,0.00007575261,0.00006649544,0.00002766634,0.0001942115,0.000008511659,0.0005005651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008437524,"threshold_uncertainty_score":0.002439797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009771777063745097,"score_gpt":0.2242536374878354,"score_spread":0.2144818604240903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}