{"id":"W2073537750","doi":"10.1038/nn.2941","title":"Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction","year":2011,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Neuroendocrine regulation and behavior","field":"Psychology","cited_by":117,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; Georgia Clinical and Translational Science Alliance; National Institute on Drug Abuse; National Institute on Aging; National Institutes of Health; National Institute of Dental and Craniofacial Research; Louise and Alan Edwards Foundation","keywords":"Vasopressin; Desmopressin; Analgesic; Medicine; Neuropeptide; Capsaicin; Single-nucleotide polymorphism; Pharmacology; Neuroscience; Receptor; Psychology; Internal medicine; Gene; Biology; Genetics; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002735325,0.0004508974,0.0004029334,0.0004826307,0.0003102752,0.0006075401,0.0004105066,0.0004135853,0.003040921],"category_scores_gemma":[0.000682509,0.0003713461,0.0004170078,0.000198775,0.0007144045,0.0003772038,0.0006424029,0.0007403441,0.0002711029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002936373,"about_ca_system_score_gemma":0.0003423931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006850965,"about_ca_topic_score_gemma":0.001097623,"domain_scores_codex":[0.9995632,0.0001134498,0.00001498768,0.0001189663,0.00009696442,0.0000924263],"domain_scores_gemma":[0.9993723,0.0002002278,0.0001672977,0.00005415933,0.00005706063,0.0001490289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001461785,0.0002188261,0.01357753,0.00005266793,0.00009271001,0.0004753767,0.0002350713,0.000129908,0.9720191,0.001227209,0.0003176543,0.01019226],"study_design_scores_gemma":[0.0002143335,0.001296881,0.8981866,0.00003908961,0.0001844084,0.00128853,0.0003828545,0.001480659,0.09289173,0.001663324,0.002294979,0.0000765947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939879,0.00109678,0.002037639,0.0003540051,0.00006584711,0.00001376089,0.0002084574,0.00005551046,0.002180018],"genre_scores_gemma":[0.9935648,0.0008582601,0.001566022,0.000237622,0.00004536246,0.00004658743,0.0001844736,0.0000508335,0.003446122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003040921,"threshold_uncertainty_score":0.01017284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02848555821556393,"score_gpt":0.2945630465918869,"score_spread":0.2660774883763229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}