{"id":"W2073605475","doi":"10.1097/cad.0b013e32832ae55f","title":"The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells","year":2009,"lang":"en","type":"article","venue":"Anti-Cancer Drugs","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute","keywords":"Apoptosis; Annexin; Caspase; Programmed cell death; Cancer cell; Cell biology; Biology; Cancer research; Chemistry; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002552171,0.0002023956,0.0001804635,0.00003892497,0.0001177733,0.00004370263,0.0002970028,0.00007426812,0.00005198804],"category_scores_gemma":[0.00003632735,0.0001428555,0.00007842073,0.0001684657,0.00005183195,0.000006588505,0.0001772018,0.0001763629,0.0000132923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002493892,"about_ca_system_score_gemma":0.00006120873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006837255,"about_ca_topic_score_gemma":0.0004508602,"domain_scores_codex":[0.9987152,0.00004648844,0.0002347605,0.0004420881,0.000168574,0.0003929174],"domain_scores_gemma":[0.9993371,0.00001221631,0.00009196345,0.0004204854,0.0000727685,0.00006543788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001211988,0.0001172604,0.001842186,0.00002185979,0.0000347288,0.000005767426,0.00004669338,0.00002839514,0.9507459,0.00006718463,0.004421255,0.04254756],"study_design_scores_gemma":[0.0005591621,0.0001774687,0.006658269,0.00001402433,0.00001300071,0.000005560653,0.00004239855,0.00004697295,0.9665404,0.0001057845,0.02560288,0.0002341021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921989,0.001676068,0.00000182045,0.003941975,0.0002747294,0.0003162809,0.00001472308,0.00001733957,0.001558205],"genre_scores_gemma":[0.9907345,0.003372015,0.00007870523,0.0007757001,0.0004074554,0.00002464871,0.00004202901,0.00001892664,0.004546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04231346,"threshold_uncertainty_score":0.582548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005415570056929603,"score_gpt":0.239556438257086,"score_spread":0.2341408682001564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}