{"id":"W2073677646","doi":"10.1016/j.imlet.2010.09.003","title":"Adenoviral vectors stimulate innate immune responses in macrophages through cross-talk with epithelial cells","year":2010,"lang":"en","type":"article","venue":"Immunology Letters","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Macrophage; Innate immune system; Inflammation; Immune system; Cell biology; Biology; Cell culture; In vitro; In vivo; Immunology; Lipopolysaccharide; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005465592,0.0005508515,0.0003384945,0.0004199416,0.0003205353,0.0007873058,0.0002345959,0.0007032445,0.002431919],"category_scores_gemma":[0.0002591649,0.0002944362,0.0006069584,0.0002237135,0.0003491506,0.0005281873,0.0005766263,0.001377176,0.000782328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000349664,"about_ca_system_score_gemma":0.000221066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001728144,"about_ca_topic_score_gemma":0.0002265266,"domain_scores_codex":[0.9993868,0.0001828082,0.00004063259,0.00007739781,0.0001475283,0.0001648625],"domain_scores_gemma":[0.9997925,0.00009653857,0.00002627838,0.00003153258,0.00001985439,0.00003334439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002473451,0.00004361859,0.0001084599,0.00005645101,0.000008768283,0.00006625104,0.00002421848,0.00002519027,0.9972588,0.0003689692,0.00006398996,0.001727949],"study_design_scores_gemma":[0.00005293061,0.0003791242,0.002184623,0.00001157035,0.00002361607,0.0002477416,0.00007501557,0.0003838049,0.9932673,0.0002298374,0.003139138,0.000005344665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9703223,0.01149364,0.009337101,0.001001303,0.0003611209,0.0001015176,0.0002966808,0.0001944858,0.006891808],"genre_scores_gemma":[0.9872738,0.002618039,0.00411745,0.0004022592,0.0001122789,0.0001033889,0.0003126172,0.00003693681,0.005023201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002431919,"threshold_uncertainty_score":0.008135617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008797895767673928,"score_gpt":0.286748244195131,"score_spread":0.2779503484274571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}