{"id":"W2073691055","doi":"10.4161/auto.26864","title":"Characterization of early autophagy signaling by quantitative phosphoproteomics","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Phosphoproteomics; Autophagy; Phosphorylation; Biology; Cell biology; PI3K/AKT/mTOR pathway; Protein phosphorylation; Signal transduction; Mechanistic target of rapamycin; Quantitative proteomics; Autophagy-related protein 13; BAG3; TOR signaling; Proteomics; Biochemistry; Protein kinase A; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003517294,0.0005484311,0.0005973365,0.001342202,0.0003419453,0.0005141253,0.0004300312,0.0003036301,0.001782748],"category_scores_gemma":[0.0003721426,0.0002377273,0.0004285987,0.001225654,0.0002318387,0.0004481188,0.0002569864,0.0008226822,0.000612693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003108386,"about_ca_system_score_gemma":0.0002688689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005522476,"about_ca_topic_score_gemma":0.001000261,"domain_scores_codex":[0.9997754,0.00002096682,0.00001732321,0.00005683962,0.00008662786,0.00004290844],"domain_scores_gemma":[0.9997714,0.00006493189,0.00005255803,0.0000220792,0.00005715281,0.00003187079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001310002,0.00002076915,0.0004835989,0.0001003628,0.00001525297,0.00003702791,0.00001454219,0.0002434062,0.9966733,0.0001075164,0.00007811429,0.002095018],"study_design_scores_gemma":[0.00001375586,0.0001202045,0.02724734,0.000009479786,0.00005196018,0.0004119267,0.00004395251,0.006758662,0.9622983,0.0003533592,0.002666133,0.00002489525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8969249,0.003915567,0.07905647,0.0002137931,0.00006655438,0.0002153614,0.01558433,0.0007067475,0.003316246],"genre_scores_gemma":[0.8817834,0.004218113,0.09410744,0.0001919925,0.00005731086,0.0006793042,0.01526371,0.0002473819,0.003451397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001782748,"threshold_uncertainty_score":0.005963862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01167032918244216,"score_gpt":0.2582079750171267,"score_spread":0.2465376458346845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}