{"id":"W2073743133","doi":"10.1371/journal.pone.0002119","title":"The Nod-Like Receptor (NLR) Family: A Tale of Similarities and Differences","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":421,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Österreichischen Akademie der Wissenschaften","keywords":"Biology; Innate immune system; Apoptosome; Protein family; Leucine-rich repeat; Effector; Pyrin domain; Cell biology; Computational biology; Genetics; Pattern recognition receptor; Signal transduction; Receptor; Caspase; Inflammasome; Gene; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005202187,0.0003390229,0.0004803473,0.0004824985,0.0004561219,0.001405373,0.0005513327,0.0006365117,0.001727474],"category_scores_gemma":[0.0003541764,0.0001224317,0.0002360829,0.0005740501,0.0008470325,0.00158437,0.001183297,0.001266973,0.0007211909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003413081,"about_ca_system_score_gemma":0.0005086443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002786599,"about_ca_topic_score_gemma":0.000260927,"domain_scores_codex":[0.9997967,0.00003896545,0.00001314117,0.00004306851,0.00007584024,0.00003236433],"domain_scores_gemma":[0.9998907,0.00001519906,0.00001730996,0.00001258631,0.00002703276,0.00003718842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006547243,0.0001271082,0.008341663,0.001729886,0.00021914,0.002836973,0.002696537,0.002074047,0.1625071,0.08812078,0.03030171,0.7003903],"study_design_scores_gemma":[0.00004152957,0.0003900389,0.009208412,0.0004429589,0.00008158982,0.007503305,0.001579029,0.001999412,0.01238659,0.0498433,0.9164316,0.00009221246],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2394772,0.5621341,0.11088,0.03402196,0.003460598,0.0002495687,0.001412444,0.001940532,0.04642349],"genre_scores_gemma":[0.6011764,0.2645753,0.08628249,0.01120156,0.001564531,0.0002028771,0.002122363,0.0002137641,0.0326607],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001727474,"threshold_uncertainty_score":0.005778909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03520734068416954,"score_gpt":0.1960080329289129,"score_spread":0.1608006922447434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}