{"id":"W2073748012","doi":"10.1021/jp068424o","title":"The Effect of Charge on the Volume Change of DNA Binding with Intercalator DAPP","year":2007,"lang":"en","type":"letter","venue":"The Journal of Physical Chemistry B","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Intercalation (chemistry); DNA; Volume (thermodynamics); Ligand (biochemistry); Charge (physics); Biophysics; Chemical physics; Crystallography; Thermodynamics; Receptor; Inorganic chemistry; Biochemistry; Biology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003688874,0.0003389891,0.0002988971,0.0001664627,0.0002227022,0.0005013893,0.0005519378,0.0004294057,0.001657102],"category_scores_gemma":[0.001526845,0.000158727,0.000129009,0.0001727578,0.0007027094,0.0004529516,0.0003769959,0.0005217424,0.0002839984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005072982,"about_ca_system_score_gemma":0.0001611258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004684306,"about_ca_topic_score_gemma":0.0003243873,"domain_scores_codex":[0.9995284,0.0001157707,0.00001156114,0.0000716667,0.000206046,0.00006665548],"domain_scores_gemma":[0.9991972,0.0005202469,0.00009514276,0.00002953987,0.00008237862,0.00007546867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002001348,0.00001678635,0.0004693723,0.00004388457,0.000009909598,0.000139216,0.00006573771,0.0003269619,0.9951977,0.0003187671,0.00006556648,0.003145965],"study_design_scores_gemma":[0.0000230629,0.0003221848,0.003596326,0.000004411835,0.000008996702,0.0002478845,0.00005497815,0.00304251,0.9917383,0.0002261955,0.0007204775,0.00001475964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953739,0.0007588814,0.001956488,0.0002196185,0.00003313613,0.00001180028,0.00005698403,0.00003628065,0.001552863],"genre_scores_gemma":[0.9987092,0.0001872533,0.0005170404,0.00008931971,0.0000115553,0.00001226283,0.00005654676,0.00001160249,0.0004051425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001657102,"threshold_uncertainty_score":0.00554353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00817372106763177,"score_gpt":0.2287822812013059,"score_spread":0.2206085601336742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}