{"id":"W2073760752","doi":"10.1016/s0969-2126(01)00656-6","title":"Structure of E. coli 5′-methylthioadenosine/S-adenosylhomocysteine Nucleosidase Reveals Similarity to the Purine Nucleoside Phosphorylases","year":2001,"lang":"en","type":"article","venue":"Structure","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Stereochemistry; Dimer; Nucleoside; Biochemistry; Transferase; Hydrolase; Chemistry; Active site; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001246394,0.0003374375,0.0003396423,0.00006633478,0.000176456,0.00004750664,0.0007726555,0.0003711605,0.0004139229],"category_scores_gemma":[0.0003874017,0.0002352317,0.0001750389,0.0004445961,0.0002223231,0.000006097234,0.0004799032,0.0003991329,0.000009178408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002338232,"about_ca_system_score_gemma":0.00008045931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009733983,"about_ca_topic_score_gemma":0.0001646997,"domain_scores_codex":[0.997896,0.0001297726,0.0003776596,0.0006024147,0.0004582984,0.000535876],"domain_scores_gemma":[0.9983342,0.00002607711,0.0001300617,0.0009617819,0.0002741847,0.0002737256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003426972,0.00003827547,0.0009341169,0.00005577133,0.0000825155,0.00002696433,0.00005700029,0.00006427494,0.9796085,0.0001414577,0.01731989,0.001328525],"study_design_scores_gemma":[0.0005877908,0.0003348861,0.007332653,0.0000317047,0.0000376391,0.0001200567,0.00005170334,0.000007372977,0.9303699,0.0006193761,0.06022191,0.0002850057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993578,0.001922476,0.0001550316,0.002778441,0.0001688175,0.0006135058,0.0005261568,0.00002118217,0.0002364108],"genre_scores_gemma":[0.9961101,0.0001395396,0.0008683026,0.001445248,0.0005004129,0.000009900679,0.0002125211,0.0000510287,0.0006629235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04923862,"threshold_uncertainty_score":0.9592472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008352305441481259,"score_gpt":0.2627045409189603,"score_spread":0.254352235477479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}