{"id":"W2073760752","doi":"10.1016/s0969-2126(01)00656-6","title":"Structure of E. coli 5′-methylthioadenosine/S-adenosylhomocysteine Nucleosidase Reveals Similarity to the Purine Nucleoside Phosphorylases","year":2001,"lang":"en","type":"article","venue":"Structure","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Stereochemistry; Dimer; Nucleoside; Biochemistry; Transferase; Hydrolase; Chemistry; Active site; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007702217,0.0002925637,0.0002706677,0.0001523456,0.0002551475,0.0005324226,0.0002137418,0.0003694093,0.00108249],"category_scores_gemma":[0.0001841226,0.0001715881,0.0002074333,0.0002598793,0.0002020056,0.0001990846,0.0001004074,0.0006570531,0.0006469523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005069819,"about_ca_system_score_gemma":0.0004815203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003235068,"about_ca_topic_score_gemma":0.002721284,"domain_scores_codex":[0.99997,0.000004961843,0.000001604365,0.000007798277,0.000007901601,0.000007854854],"domain_scores_gemma":[0.9999019,0.00001824868,0.00002183876,0.000009238353,0.00001613596,0.00003269894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007180293,0.00007426032,0.001156817,0.00009901664,0.00001568186,0.00062956,0.000152197,0.001327154,0.9863966,0.001640997,0.0003902086,0.00739962],"study_design_scores_gemma":[0.0001074171,0.0008974072,0.03996322,0.00005184286,0.0001187984,0.002187331,0.0003725756,0.01378205,0.9177646,0.001750691,0.02293698,0.00006696736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901091,0.001715104,0.003797718,0.0003101765,0.00004369421,0.00001862104,0.0004629039,0.0001545663,0.003388122],"genre_scores_gemma":[0.9889909,0.0009200907,0.004272668,0.0001046843,0.00001443595,0.00001015261,0.002078151,0.00002651424,0.003582362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003235068,"threshold_uncertainty_score":0.006432474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008352305441481259,"score_gpt":0.2627045409189603,"score_spread":0.254352235477479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}