{"id":"W2073771642","doi":"10.1016/j.molcel.2014.08.015","title":"New pROSpects for PTP1B: micro-Managing Oncogene-Induced Senescence","year":2014,"lang":"en","type":"letter","venue":"Molecular Cell","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Biology; Senescence; Oncogene; Cell biology; Cellular senescence; Computational biology; Genetics; Cell; Cell cycle; Gene; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002670266,0.0008456777,0.0009234243,0.0004611263,0.001006626,0.002726395,0.001308575,0.01285924,0.004769216],"category_scores_gemma":[0.002972831,0.0003772628,0.0006988362,0.0003129191,0.003074598,0.004329951,0.001250869,0.01236907,0.002373518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001639527,"about_ca_system_score_gemma":0.0008743765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002236645,"about_ca_topic_score_gemma":0.0005761549,"domain_scores_codex":[0.9993721,0.000145791,0.00005225845,0.0001148698,0.0002045084,0.0001104965],"domain_scores_gemma":[0.9990395,0.0004586097,0.00008653801,0.00008870534,0.000127228,0.0001994439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001457579,0.0005163579,0.001268578,0.000811932,0.00009868346,0.006059993,0.0002639733,0.001098946,0.02729031,0.1332004,0.6172569,0.2106764],"study_design_scores_gemma":[0.0004723997,0.0005491712,0.0007035168,0.0001387766,0.00005376342,0.003800745,0.0002386123,0.001882562,0.007634262,0.1183099,0.8661472,0.00006910771],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005521999,0.09159476,0.009321889,0.8431414,0.03980433,0.00005974469,0.0001003412,0.0003795344,0.010076],"genre_scores_gemma":[0.1215287,0.116674,0.01405938,0.4985983,0.1939812,0.0004661986,0.0001976141,0.0001700927,0.05432448],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01285924,"threshold_uncertainty_score":0.01595455,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01025496948915683,"score_gpt":0.2332955663944539,"score_spread":0.223040596905297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}