{"id":"W2073809564","doi":"10.1016/j.molmed.2005.11.001","title":"Friend or foe? Antimicrobial peptides trigger pathogen virulence","year":2005,"lang":"en","type":"article","venue":"Trends in Molecular Medicine","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Antimicrobial; Virulence; Antimicrobial peptides; Microbiology; Salmonella; Pathogen; Biology; Immune system; Innate immune system; Antibiotics; Immunity; Bacteria; Gene; Immunology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002917143,0.0003211913,0.0005434507,0.0004108176,0.0001155291,0.00001184504,0.0003179373,0.0002499674,0.003277822],"category_scores_gemma":[0.00008778052,0.0002353486,0.0001161502,0.0004342037,0.0005778429,0.0001451091,0.00009910353,0.0004130724,0.0002788899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000576387,"about_ca_system_score_gemma":0.00004178815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000187336,"about_ca_topic_score_gemma":0.0001765208,"domain_scores_codex":[0.9982489,0.0001502544,0.000485528,0.0004676784,0.00007019363,0.0005773886],"domain_scores_gemma":[0.9993358,0.00008264174,0.0001333959,0.0003678298,0.00003930224,0.00004100329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002492883,0.000142226,0.0001687996,0.00001488994,0.00005969524,0.000136975,0.0007818766,0.00003046735,0.9226508,0.0003757915,0.02412059,0.05126867],"study_design_scores_gemma":[0.007802395,0.0007435454,0.003779694,0.0005293436,0.0001631017,0.00061469,0.0007123994,0.00002711165,0.6898739,0.000115194,0.2947776,0.0008609783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9737625,0.003466759,0.00115875,0.008053873,0.0007859219,0.000230254,0.00008205808,0.0001661978,0.01229366],"genre_scores_gemma":[0.9819214,0.0002272001,0.0009191438,0.001728531,0.0001860261,0.00001253079,0.0001795634,0.00003780342,0.01478782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2706571,"threshold_uncertainty_score":0.9976333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01628253419182259,"score_gpt":0.274083251998905,"score_spread":0.2578007178070824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}