{"id":"W2073845633","doi":"10.1007/s100380170072","title":"Single-nucleotide polymorphisms of the nuclear lamina proteome","year":2001,"lang":"en","type":"article","venue":"Journal of Human Genetics","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials","funders":"Medical Research Council; Canadian Diabetes Association; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"LMNA; Lamin; Nuclear lamina; Biology; Genetics; Single-nucleotide polymorphism; Inner membrane; Gene; Nuclear protein; Genotype; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001052316,0.00009246464,0.0001271658,0.00003962772,0.00007816458,0.00001489195,0.0002583182,0.00008842375,0.00006183508],"category_scores_gemma":[0.00001901068,0.00006533336,0.0001526975,0.0000700361,0.00009871623,0.000003244214,0.00007578717,0.0001191318,0.00000287588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001175487,"about_ca_system_score_gemma":0.00002500476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001536751,"about_ca_topic_score_gemma":0.000007410953,"domain_scores_codex":[0.9992667,0.00004162934,0.000301355,0.00008892464,0.000180394,0.0001210382],"domain_scores_gemma":[0.9992187,0.000002804848,0.0003481948,0.0002522434,0.0001324063,0.00004562356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005808959,0.00005025975,0.002578724,0.00000582257,0.00003913254,0.000004483328,0.00005767518,0.00002413542,0.9926634,0.00003158368,0.002656735,0.001829952],"study_design_scores_gemma":[0.0009660378,0.002413918,0.06516863,0.00005337277,0.0001134488,0.0005618013,0.0001567078,0.00001406821,0.6427705,0.0006843368,0.286876,0.0002212424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973604,0.0004107953,0.00004718738,0.0001550341,0.0003528874,0.00007422214,0.000001782556,0.000002068197,0.001595601],"genre_scores_gemma":[0.9977899,0.00008307329,0.0005547171,0.0001629032,0.0006594369,2.344538e-7,0.0000011696,0.00002369244,0.0007249202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3498929,"threshold_uncertainty_score":0.2664217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01124943172521368,"score_gpt":0.2219609837300662,"score_spread":0.2107115520048526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}