{"id":"W2073879634","doi":"10.4161/chan.5.3.15873","title":"Mechanism of K<sup>+</sup> /Na<sup>+</sup>selectivity in potassium channels from the perspective of the non-selective bacterial channel NaK","year":2011,"lang":"en","type":"letter","venue":"Channels","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research","keywords":"Selectivity; Chemistry; Potassium channel; Ion channel; NAK; Conductance; Biophysics; Ion; Potassium; Biochemistry; Biology; Physics; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006788709,0.0009275863,0.001086079,0.0002939936,0.0002704881,0.00005761924,0.00120106,0.002082445,0.0001996922],"category_scores_gemma":[0.000387237,0.0006780448,0.0007703768,0.000695428,0.0004654969,0.00003562581,0.0005339368,0.001593039,0.00002018927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00024801,"about_ca_system_score_gemma":0.0004681276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001583791,"about_ca_topic_score_gemma":0.00005564976,"domain_scores_codex":[0.9952837,0.0008152181,0.0009155698,0.001405352,0.0006967621,0.0008834057],"domain_scores_gemma":[0.996551,0.0001776544,0.000943911,0.001288838,0.00093466,0.0001039796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00442737,0.001675763,0.0003903722,0.0006763155,0.003653851,0.00006964448,0.05418503,0.02144952,0.1361606,0.001324612,0.7750899,0.0008970427],"study_design_scores_gemma":[0.006095626,0.002069034,0.0008891347,0.0008889526,0.0006033757,0.00007953069,0.00628612,0.0238559,0.9013475,0.01714987,0.03796168,0.002773276],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8375604,0.001514578,0.01449744,0.1077638,0.01810716,0.009931793,0.004636468,0.00017255,0.005815784],"genre_scores_gemma":[0.9722244,0.000109927,0.0000342456,0.0136062,0.01092075,0.0002841973,0.0009317403,0.0001749896,0.001713614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7651868,"threshold_uncertainty_score":0.9995671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01611448773223761,"score_gpt":0.2240046131445793,"score_spread":0.2078901254123416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}