{"id":"W2073912003","doi":"10.1016/j.healun.2015.01.003","title":"The role of the endothelin-1 pathway as a biomarker for donor lung assessment in clinical ex vivo lung perfusion","year":2015,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; Toronto Rehabilitation Institute; University Health Network","funders":"","keywords":"Medicine; Lung transplantation; Transplantation; Lung; Perfusion; Endothelin 1; Nitric oxide; Ex vivo; Internal medicine; Urology; In vivo; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004249396,0.0001103124,0.0002916848,0.00006362678,0.0001415398,0.00001931521,0.0001131385,0.00007275878,0.000009662252],"category_scores_gemma":[0.00006903194,0.00004897117,0.0001746856,0.00009837005,0.00009284184,0.0000975988,0.000006654387,0.0002833515,2.994345e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003377787,"about_ca_system_score_gemma":0.0002648226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006569357,"about_ca_topic_score_gemma":0.00008103465,"domain_scores_codex":[0.998165,0.0005287217,0.0007264447,0.00008899733,0.0003397643,0.0001510444],"domain_scores_gemma":[0.9979809,0.001379826,0.0002594328,0.0001389282,0.0001566321,0.00008427133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01225906,0.0002599599,0.8271394,0.0005337259,0.0002752998,0.00001788399,0.01162047,0.00007236232,0.1303221,0.001031595,0.0004511537,0.01601704],"study_design_scores_gemma":[0.008777165,0.000711498,0.950383,0.0008090354,0.001245097,0.001030569,0.002925965,0.01145307,0.01874857,0.001177743,0.002597187,0.000141075],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988363,0.002430215,0.004152239,0.003739749,0.0004013792,0.0006148986,0.00002401657,0.00000487567,0.0002696218],"genre_scores_gemma":[0.9941256,0.002702228,0.002692184,0.0002139038,0.0001364429,0.00000587636,0.000004136265,0.00001230858,0.000107324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1232437,"threshold_uncertainty_score":0.1996986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03324602925896264,"score_gpt":0.3836649610569555,"score_spread":0.3504189317979929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}