{"id":"W2073923516","doi":"10.1002/1098-2280(2000)35:4<319::aid-em6>3.0.co;2-h","title":"The tumor promoter TPA enhances benzo[a]pyrene and benzo[a]pyrene diolepoxide mutagenesis in Big Blue� mouse skin","year":2000,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Environmental Health Sciences","keywords":"Benzo(a)pyrene; Molecular biology; Carcinogen; Mutagenesis; DNA; Chemistry; DNA damage; Mutant; Cell growth; Mutagen; Carcinogenesis; DNA repair; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002786026,0.0004608795,0.0003105043,0.00006873097,0.0002727662,0.00008669253,0.0002972056,0.0001867915,0.0001038269],"category_scores_gemma":[0.000020052,0.0003861086,0.000145398,0.00008848141,0.0003173767,0.00001496326,0.0002917998,0.0001222222,0.00003326332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000039493,"about_ca_system_score_gemma":0.00002455939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006664491,"about_ca_topic_score_gemma":0.000104169,"domain_scores_codex":[0.9976047,0.0001850656,0.0004121228,0.0009205514,0.000297658,0.0005798548],"domain_scores_gemma":[0.9990523,0.00002657181,0.0001018673,0.0005993185,0.000006283384,0.0002136916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001074043,0.0001338524,0.0006352246,0.00001741171,0.00008469831,0.00008912233,0.0001361473,0.00005067197,0.9393689,0.000008929182,0.00002400578,0.05934361],"study_design_scores_gemma":[0.0008143445,0.0003850251,0.006712615,0.00001679053,0.00006143063,0.0000977632,0.0003185041,0.00007611156,0.9817918,0.00005877763,0.009165998,0.0005008563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916232,0.007287052,0.000156141,0.000129275,0.0000747651,0.0004936509,0.00006039717,0.00002493507,0.0001505376],"genre_scores_gemma":[0.9921643,0.004091292,0.0005983349,0.0004822221,0.0001019078,0.0001566756,0.0001057402,0.00008300652,0.002216578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05884275,"threshold_uncertainty_score":0.9998591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00282819680611404,"score_gpt":0.1794144404817046,"score_spread":0.1765862436755905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}