{"id":"W2073927954","doi":"10.1186/s12882-015-0047-z","title":"Urate lowering therapy to improve renal outcomes in patients with chronic kidney disease: systematic review and meta-analysis","year":2015,"lang":"en","type":"review","venue":"BMC Nephrology","topic":"Gout, Hyperuricemia, Uric Acid","field":"Medicine","cited_by":176,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; London Health Sciences Centre","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Kidney disease; Internal medicine; Renal function; Randomized controlled trial; Hyperuricemia; Meta-analysis; Creatinine; Allopurinol; Nephrology; Proteinuria; Uric acid; Blood pressure; Adverse effect; Intensive care medicine; Kidney","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01024716,0.002404189,0.01931544,0.005053571,0.0005224835,0.002848479,0.001893216,0.002074848,0.003743412],"category_scores_gemma":[0.02547438,0.001208938,0.03155129,0.005816101,0.000616536,0.001306547,0.001276257,0.001871397,0.0002541174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002969544,"about_ca_system_score_gemma":0.003434657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009171347,"about_ca_topic_score_gemma":0.01874496,"domain_scores_codex":[0.9929675,0.003547334,0.001797765,0.0006511098,0.0007896033,0.0002466072],"domain_scores_gemma":[0.9868141,0.009857798,0.002006625,0.0002808612,0.0008590764,0.0001813852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001962742,0.00002644108,0.001954116,0.43443,0.5497474,0.00007387711,0.00006654861,0.0005380131,0.0001501823,0.0001128999,0.000660297,0.01027743],"study_design_scores_gemma":[0.000791492,0.0001985335,0.002510043,0.03096122,0.9637159,0.0000671473,0.00003037844,0.0001947444,0.00008209527,0.0001549625,0.001275304,0.00001820746],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00392526,0.9943902,0.0003462461,0.0001917675,0.0001256644,0.0003303859,0.0004471436,0.00002523505,0.0002181299],"genre_scores_gemma":[0.1289622,0.8655677,0.001933951,0.000968033,0.0002534104,0.001260388,0.0007173225,0.00002662539,0.0003102627],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01931544,"threshold_uncertainty_score":0.05419278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05090041905683505,"score_gpt":0.3312999688198323,"score_spread":0.2803995497629972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}