{"id":"W2073980604","doi":"10.1016/s0014-827x(02)00029-0","title":"Synthesis and in vitro antifungal and cytotoxicity evaluation of substituted 4,5-dihydronaphtho[1,2-d][1,2,3]thia(or selena)diazoles","year":2003,"lang":"en","type":"article","venue":"Il Farmaco","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Toxicity; Nuclear chemistry; Antifungal; Semicarbazone; Cytotoxicity; In vitro; Cryptococcus neoformans; Yield (engineering); Medicinal chemistry; Organic chemistry; Microbiology; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001646008,0.000256108,0.0002491204,0.00019399,0.0001627597,0.0001289839,0.0002935329,0.0001987339,0.001164516],"category_scores_gemma":[0.0001341592,0.0001234824,0.0001631545,0.0001702619,0.0001177417,0.0001444878,0.0001116207,0.0002070171,0.0003656944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002268177,"about_ca_system_score_gemma":0.0002458425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004533944,"about_ca_topic_score_gemma":0.00150346,"domain_scores_codex":[0.9999048,0.00002659351,0.0000127403,0.00001485406,0.00002391327,0.00001712017],"domain_scores_gemma":[0.999925,0.00001689076,0.00001679712,0.00001054879,0.00001601377,0.00001469918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001135164,0.00002423825,0.00003594987,0.00005715874,0.000003170745,0.00008599279,0.00002059389,0.0001984821,0.9973466,0.000123572,0.0000450927,0.001945469],"study_design_scores_gemma":[0.00002379932,0.0006472008,0.0005061913,0.000006464044,0.00001280658,0.0001526881,0.00001261272,0.000249959,0.9959566,0.00002902465,0.002398102,0.000004636637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787459,0.005479276,0.008681256,0.00009320695,0.00005558035,0.0001274849,0.0009869604,0.0001002202,0.005730186],"genre_scores_gemma":[0.9845549,0.003218673,0.006443105,0.00003952631,0.00001668817,0.00005705893,0.0009071437,0.00001892941,0.004743873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001164516,"threshold_uncertainty_score":0.0038957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04396568050044788,"score_gpt":0.2859143614832565,"score_spread":0.2419486809828086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}