{"id":"W2073980604","doi":"10.1016/s0014-827x(02)00029-0","title":"Synthesis and in vitro antifungal and cytotoxicity evaluation of substituted 4,5-dihydronaphtho[1,2-d][1,2,3]thia(or selena)diazoles","year":2003,"lang":"en","type":"article","venue":"Il Farmaco","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Toxicity; Nuclear chemistry; Antifungal; Semicarbazone; Cytotoxicity; In vitro; Cryptococcus neoformans; Yield (engineering); Medicinal chemistry; Organic chemistry; Microbiology; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001117882,0.0001879683,0.0003516026,0.00006103331,0.00006483638,0.00002059796,0.0000879295,0.0001905584,0.0005439684],"category_scores_gemma":[0.001080967,0.0001375426,0.00004878845,0.0001409784,0.0001654609,0.0001082594,0.00004025907,0.0001702647,0.000002280669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005212817,"about_ca_system_score_gemma":0.00006466933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006829944,"about_ca_topic_score_gemma":0.00003909406,"domain_scores_codex":[0.9985862,0.0002333321,0.000289851,0.0003582896,0.000293049,0.0002393133],"domain_scores_gemma":[0.9988979,0.0006647761,0.000124991,0.0001546332,0.00007363626,0.00008404028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002487179,0.0001891082,0.02501818,0.00008306564,0.00003209879,0.000004715163,0.0000360499,0.00001406149,0.9538158,0.00002548214,0.00000877848,0.02052394],"study_design_scores_gemma":[0.0005646379,0.000009012655,0.03283545,0.00005298208,0.0000775883,0.00001625727,0.00007933719,0.002122426,0.9637155,0.0001296964,0.0002118241,0.0001852832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969819,0.0005004279,0.000006229656,0.00005152592,0.00003006535,0.0001245447,0.00008089899,0.00002987356,0.002194588],"genre_scores_gemma":[0.9994331,0.0002431003,0.00019625,0.00002480682,0.00002944284,0.00003982193,0.000004580322,0.00001005729,0.00001881886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02033865,"threshold_uncertainty_score":0.5956073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04396568050044788,"score_gpt":0.2859143614832565,"score_spread":0.2419486809828086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}