{"id":"W2074007950","doi":"10.1038/ajg.2013.441","title":"Drug Therapies and the Risk of Malignancy in Crohn's Disease: Results From the TREAT™ Registry","year":2014,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"Janssen Biotech","keywords":"Medicine; Internal medicine; Hazard ratio; Crohn's disease; Infliximab; Malignancy; Incidence (geometry); Population; Cancer registry; Discontinuation; Proportional hazards model; Cohort; Inflammatory bowel disease; Disease; Cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001129383,0.0001325434,0.0002952346,0.00002464661,0.00007197564,0.0000135417,0.0005182298,0.00001888701,0.000003169711],"category_scores_gemma":[0.0004336324,0.00006017082,0.0001489625,0.00004163487,0.001672736,0.000004398904,0.0001041097,0.0001915715,5.59557e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006406775,"about_ca_system_score_gemma":0.00003829664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001509163,"about_ca_topic_score_gemma":0.0002115938,"domain_scores_codex":[0.9974039,0.001711305,0.0004223767,0.0001476526,0.0001222137,0.0001925432],"domain_scores_gemma":[0.9978315,0.0002385585,0.001260457,0.0005337166,0.00006903907,0.0000666997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1249764,0.00009070036,0.8661574,0.000006760957,0.0003854327,0.00008763255,0.001330458,0.0003529867,0.001710694,0.00009086065,0.00184463,0.002966116],"study_design_scores_gemma":[0.003282385,0.0004656914,0.9943063,0.00002639088,0.0001182336,0.00003383188,0.0006337379,0.00004782436,0.00007535816,0.0006390713,0.0003282289,0.00004299993],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944598,0.0005479407,0.0001531364,0.004565561,0.00005899352,0.0001021186,0.00007962771,0.000001532725,0.00003126731],"genre_scores_gemma":[0.997785,0.0008489095,0.00009096996,0.001000672,0.000222574,0.000005040414,0.000005467582,0.00001184079,0.0000294768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1281489,"threshold_uncertainty_score":0.6163266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003075984081980354,"score_gpt":0.2033876395282829,"score_spread":0.2003116554463026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}