{"id":"W2074028857","doi":"10.1111/j.1747-0285.2006.00378.x","title":"Aza‐scanning of the Potent Melanocortin Receptor Agonist Ac‐His‐<scp>d</scp>‐Phe‐Arg‐Trp‐NH<sub>2</sub>","year":2006,"lang":"en","type":"article","venue":"Chemical Biology & Drug Design","topic":"Biochemical Analysis and Sensing Techniques","field":"Nursing","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal; Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Melanocortin; Tetrapeptide; Melanocortin receptor; Peptide; Melanocortin 4 receptor; Amino acid; Chemistry; Peptide sequence; Receptor; Agonist; Biochemistry; Stereochemistry; Melanocortin 3 receptor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000585335,0.0004363967,0.0007496651,0.00009285424,0.0002327407,0.00004245855,0.0007177368,0.0006076672,0.00001413186],"category_scores_gemma":[0.0006544941,0.0003117358,0.0005093597,0.0005255807,0.0009124051,0.00005250903,0.0002307625,0.0006383934,0.00003952657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001676429,"about_ca_system_score_gemma":0.00004743256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001281344,"about_ca_topic_score_gemma":0.000005280859,"domain_scores_codex":[0.9969717,0.0003766542,0.0008989842,0.0007597666,0.0002582863,0.0007346655],"domain_scores_gemma":[0.9977324,0.0007071038,0.0005311798,0.0007003886,0.0001944586,0.0001344887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005546679,0.0001538382,0.0009024543,0.00002031572,0.00005409175,0.000001595339,0.00008604332,0.000007766233,0.9221762,0.0002041083,0.07189354,0.004444527],"study_design_scores_gemma":[0.0002988741,0.00006409628,0.0002118348,0.00009650676,0.0001479182,0.00001003482,0.00004381853,0.0002338155,0.9887537,0.005892566,0.00404952,0.0001972937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927983,0.001085997,0.001997286,0.002157211,0.00035878,0.0004096769,0.00002807656,0.0002862483,0.0008784096],"genre_scores_gemma":[0.9921453,0.00003832672,0.006461126,0.0006524955,0.0003811614,0.0000286101,0.0001136625,0.00005235684,0.0001269441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06784402,"threshold_uncertainty_score":0.9999335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01144975150151162,"score_gpt":0.2244700192913201,"score_spread":0.2130202677898085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}