{"id":"W2074034082","doi":"10.1016/s0005-2736(02)00661-2","title":"Rate of biodistribution of STEALTH® liposomes to tumor and skin: influence of liposome diameter and implications for toxicity and therapeutic activity","year":2002,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":169,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Liposome; Biodistribution; Toxicity; Pharmacology; Pharmacokinetics; Chemistry; Doxorubicin; Medicine; Chemotherapy; In vitro; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006062467,0.0002624654,0.0002732112,0.0002504178,0.0001357992,0.0004224135,0.0002145726,0.0002396279,0.001412433],"category_scores_gemma":[0.0009099165,0.0002124988,0.0001919586,0.0001831518,0.0002379881,0.0004713958,0.0002413041,0.0005857027,0.0005305937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003301593,"about_ca_system_score_gemma":0.0003375314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001241839,"about_ca_topic_score_gemma":0.000445208,"domain_scores_codex":[0.9998123,0.00004771495,0.00001411612,0.00005867338,0.00002627629,0.00004100294],"domain_scores_gemma":[0.9991814,0.0004188048,0.00009853747,0.00008154939,0.0001614593,0.00005816912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009637558,0.00002827938,0.001437029,0.00006153782,0.00001188037,0.00005640484,0.0001529991,0.000338449,0.9903278,0.0002355095,0.00009897498,0.006287328],"study_design_scores_gemma":[0.000009763334,0.0002545777,0.002943106,0.000003883546,0.00001533355,0.0001115175,0.00003354289,0.001718459,0.9942708,0.00003852862,0.0005951378,0.000005442376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990028,0.001695161,0.006007526,0.00005112943,0.00001660063,0.00003451912,0.0002637251,0.00008291785,0.0018203],"genre_scores_gemma":[0.9944636,0.0006252525,0.001453741,0.00002384228,0.000004876646,0.00003980846,0.000234765,0.00007718079,0.003076966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001412433,"threshold_uncertainty_score":0.004725039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01904713346111049,"score_gpt":0.2567655248560464,"score_spread":0.2377183913949359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}