{"id":"W2074038170","doi":"10.1016/s0925-4773(01)00463-4","title":"Cloning of a novel retinoic-acid metabolizing cytochrome P450, Cyp26B1, and comparative expression analysis with Cyp26A1 during early murine development","year":2001,"lang":"en","type":"article","venue":"Mechanisms of Development","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":218,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Rhombomere; Ectoderm; Retinoic acid; Endoderm; Apical ectodermal ridge; Mesoderm; Molecular biology; Neural crest; Mesenchyme; Cell biology; Limb bud; Cellular differentiation; Embryogenesis; Embryonic stem cell; Embryo; Genetics; Gene expression; Hox gene; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002703784,0.0002953428,0.0005309902,0.0002039574,0.0001590985,0.00002098407,0.000218423,0.0001254904,0.00002040896],"category_scores_gemma":[0.00001830197,0.0002505084,0.00006961863,0.0003888076,0.00007994653,0.00001436648,0.0002561579,0.00009622223,8.278589e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003488635,"about_ca_system_score_gemma":0.0002218322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009250743,"about_ca_topic_score_gemma":0.00001665999,"domain_scores_codex":[0.9981968,0.00003670988,0.0005698909,0.0005084615,0.0003741163,0.0003140562],"domain_scores_gemma":[0.9990269,0.00001049612,0.0003734626,0.0002713021,0.0002132263,0.0001046269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002460136,0.0001169713,0.00254005,0.0001213337,0.0005575961,0.000007508595,0.00120457,0.0001822814,0.9947155,0.0001032942,0.000001411037,0.0002034783],"study_design_scores_gemma":[0.001102282,0.0001838746,0.02797909,0.0001519284,0.0001194746,0.000025295,0.0004930682,0.00002437106,0.9692184,0.00001188552,0.000368605,0.0003217688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8809845,0.0005354661,0.117967,0.000006053891,0.00001798008,0.0001950988,0.000003494753,0.0000130382,0.0002773389],"genre_scores_gemma":[0.8285869,0.0000672135,0.1709701,0.000009832867,0.00001869862,0.00004448085,0.00005124636,0.00001751091,0.0002340864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05300312,"threshold_uncertainty_score":0.9999947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01704806315684997,"score_gpt":0.2356537427524352,"score_spread":0.2186056795955852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}